Ciclo XXIV

Manchia Mirko
Chillotti C, Deiana V, Manchia M, Lampus SF, Ardau R, Severino G, Del Zompo M. Evaluation of lithium treatment response in Sardinian bipolar patients Riv Psichiatr. 2009 Jan-Feb;44(1):28-35.

ManchiaM, Congiu D, SquassinaA, LampusS, ArdauR, ChillottiC, SeverinoG, Del Zompo M, No association between lithium full responders and the DRD1, DRD2, DRD3, DAT1, 5-HTTLPR and HTR2A genes in a Sardinian sample. Psychiatry Research, 2009 Sep 30;169: 164-6.

Asuni C, Stochino ME, Cherchi A, Manchia M, CongiuD, Manconi F, Squassina, Piccardi MP, Del Zompo M, Migraine and Tumour Necrosis Factor Gene Polymorphism: An Association Study in a Sardinian Sample. Journal of Neurology, 2009 Mar; 256: 194-7.

Severino G, Mirko Manchia, Paolo Contu, Alessio Squassina, Simona Lampus, Raffaella Ardau, Caterina Chillotti, Maria Del Zompo – Association study in a Sardinian sample between Bipolar Disorder and the nuclear receptor REV-ERBα gene, a critical component of the circadian clock system. Bipolar Disorders, 2009 Feb; 11: 215–220.

Alessio Squassina, Mirko Manchia, Donatella Congiu, Giovanni Severino, Caterina Chillotti, Raffaella Ardau, Maria Paola Piccardi, Maria Del Zompo. The diacylglycerol kinase eta gene and bipolar disorder: a replication study in a Sardinian sample. Molecular Psychiatry, 2009 Apr; 14: 350-1

Mirko Manchia, Emanuela Viggiano, Arun Tiwari, Julien Renou, Umesh Jain, Vincenzo De Luca, James L. Kennedy. Smoking in Adult Attention-Deficit/Hyperactivity Disorder: interaction between 15q13 nicotinic genes and Temperament Character Inventory Scores. World Journal of Biological Psychiatry 2009 doi: 10.1080/15622970902980788.

Zai CC, Manchia M, De Luca V, Tiwari AK, Squassina A, Zai GC, Strauss J, Shaikh SA, Freeman N, Meltzer HY, Lieberman J, Le Foll B, Kennedy JL. Association study of BDNF and DRD3 genes in schizophrenia diagnosis using matched case-control and family based study designs.Prog Neuropsychopharmacol Biol Psychiatry. 2010 Dec 1;34(8):1412-8.

Squassina A, Manchia M, Del Zompo M. Pharmacogenomics of mood stabilizers in the treatment of bipolar disorder.Hum Genomics Proteomics. 2010 Aug 3;2010:159761.

Panariello F, O’Driscoll L, de Souza RP, Tiwari A, Manchia M, Kennedy J, De Luca V. Age at onset in Canadian schizophrenia patients: admixture analysis. Schizophr Res. 2010 Sep;122(1-3):278-9.

Asuni C, Manchia M, Deidda A, Stochino ME, Cherchi A, del Zompo M. Mixture analysis of age at onset in migraine without aura: evidence for three subgroups.Headache. 2010 Sep;50(8):1313-9.

Manchia M, Zai CC, Squassina A, Vincent JB, De Luca V, Kennedy JL. Mixture regression analysis on age at onset in bipolar disorder patients: investigation of the role of serotonergic genes.
Eur Neuropsychopharmacol. 2010 Sep;20(9):663-70.

Schulze TG, Alda M, Adli M, Akula N, Ardau R, Bui ET, Chillotti C, Cichon S, Czerski P, Del Zompo M, Detera-Wadleigh SD, Grof P, Gruber O, Hashimoto R, Hauser J, Hoban R, Iwata N, Kassem L, Kato T, Kittel-Schneider S, Kliwicki S, Kelsoe JR, Kusumi I, Laje G, Leckband SG, Manchia M, Macqueen G, Masui T, Ozaki N, Perlis RH, Pfennig A, Piccardi P, Richardson S, Rouleau G, Reif A, Rybakowski JK, Sasse J, Schumacher J, Severino G, Smoller JW, Squassina A, Turecki G, Young LT, Yoshikawa T, Bauer M, McMahon FJ. The International Consortium on Lithium Genetics (ConLiGen): an initiative by the NIMH and IGSLI to study the genetic basis of response to lithium treatment. Neuropsychobiology. 2010;62(1):72-8.

Squassina A, Manchia M, Manolopoulos VG, Artac M, Lappa-Manakou C, Karkabouna S, Mitropoulos K, Del Zompo M, Patrinos GP. Realities and expectations of pharmacogenomics and personalized medicine: impact of translating genetic knowledge into clinical practice.Pharmacogenomics. 2010 Aug;11(8):1149-67.

Tozzi F, Manchia M, Galwey NW, Severino G, Del Zompo M, Day R, Matthews K, Strauss J, Kennedy JL, McGuffin P, Vincent JB, Farmer A, Muglia P. Admixture analysis of age at onset in bipolar disorder.Psychiatry Res. 2011 Jan 30;185(1-2):27-32.

Squassina A, Manchia M, Borg J, Congiu D, Costa M, Georgitsi M, Chillotti C, Ardau R,
Mitropoulos K, Severino G, Del Zompo M, Patrinos GP. Evidence for association of an ACCN1
gene variant with response to lithium treatment in Sardinian patients with bipolar disorder. P
Pharmacogenomics. 2011 Oct 3. Ahead of print 2011 Nov;12(11):1559-69.

Zai CC, Manchia M, De Luca V, Tiwari AK, Chowdhury NI, Zai GC, Tong RP, Yilmaz Z, Shaikh SA, Strauss J, Kennedy JL. The brain-derived neurotrophic factor gene in suicidal behaviour: a meta-analysis. Int J Neuropsychopharmacol. 2012 Sep;15(8):1037-42.

Deiana V, Chillotti C, Manchia M, Pinna M, Ardau R, Del Zompo M, Severino G. A retrospective
case series of bipolar patients with adjunctive carbamazepine in long-term lithium treatment:
evaluation of the effectiveness. J Clin Psychopharmacol. 2011; 31: 538-40.

Squassina A*, Manchia M*, Costa M, Chillotti C, Ardau R, Del Zompo M, Severino G.
Age at onset in bipolar disorder: Investigation of the role of TaqIA polymorphism of DRD2 gene
in a Sardinian sample. Eur Psychiatry. 2011; 26: 141-3.

Souza RP, De Luca V, Manchia M, Kennedy JL. Are serotonin 3A and 3B receptor genes associated with suicidal behavior in schizophrenia subjects? Neurosci Lett. 2011; 489:137-41.
Evaluation of lithium response in episodic cluster headache: a retrospective case series.
Stochino ME, Deidda A, Asuni C, Cherchi A, Manchia M, Del Zompo M.
Headache. 2012 Jul-Aug;52(7):1171-5.

Bauer M, Glenn T, Alda M, Andreassen OA, Ardau R, Bellivier F, Berk M, Bjella TD, Bossini L, Del Zompo M, Dodd S, Fagiolini A, Frye MA, Gonzalez-Pinto A, Henry C, Kapczinski F, Kliwicki S, König B, Kunz M, Lafer B, Lopez-Jaramillo C, Manchia M, Marsh W, Martinez-Cengotitabengoa M, Melle I, Morken G, Munoz R, Nery FG, O’Donovan C, Pfennig A, Quiroz D, Rasgon N, Reif A, Rybakowski J, Sagduyu K, Simhandl C, Torrent C, Vieta E, Zetin M, Whybrow PC. Impact of sunlight on the age of onset of bipolar disorder.Bipolar Disord. 2012 Sep;14(6):654-663.

Lecca Salvatore
Mascia P, Pistis M, Justinova Z, Panlilio L, Luchicchi A, Lecca S, Scherma M, Fratta W, Fadda P, Barnes C, Redhi GH, Yasar S, Le Foll B, Tanda G, Piomelli D, Goldberg SR (2010) Blockade of nicotine reward and reinstatement by activation of alpha-type peroxisome proliferator-activated receptors. Biol.Psychiatry 2010 Aug 27.

Luchicchi A, Lecca S, Carta S, Pillolla G, Muntoni AL, Yasar S, Goldberg SR, Pistis M (2010), Effects of fatty acud amide hydrolase inhibition on neuronal responses to nicotine, cocaine and morphine in the nucleus accumbens shell and ventral tegmental area: involvement of PPAR-alpha nuclear receptors. Addict.Biol., 15(3):277-88.

Lecca S, Melis M, Luchicchi A, Ennas MG, Castelli MP, Muntoni AL and PistisM
Effects of drugs of abuse on putative rostromedial tegmental neurons, inhibitory afferents to midbrain dopamine cells.Neuropshychopharmacology 2011 [Feb;36(3):589-602]

Peddio Giuseppe
G. Marchese, B. Pittau, G. Casu, G. Peddio, G.P Spada, M. Pira, A. Deriu, F. Portesani, C. Pisu, P. Lazzari, L. Pani. A comparison of continuous subcutaneous paliperidone infusion and repeated subcutaneous injection of risperidone free-base in rats. Eur Psychiatry 2010 Mar;25(2):92-100. Epub 2009 Jul 28.
G. Marchese, B. Pittau, G. Casu, G. Peddio, G.P Spada, M. Pira, A. Deriu, F. Portesani, C. Pisu, P. Lazzari, L. Pani. A comparison of continuous subcutaneous paliperidone infusion and repeated subcutaneous injection of risperidone free-base in rats. Eur Psychiatry 2010 Mar;25(2):92-100. Epub 2009 Jul 28.

Santoru Francesca
Calza A, Sogliano C, Santoru F, Marra C, Angioni MM, Mostallino MC, Biggio G, Concas A.
Neonatal exposure to estradiol in rats influences neuroactive steroid concentrations, GABAA receptor expression, and behavioral sensitivity to anxiolytic drugs.J Neurochem. 2010 Jun;113(5):1285-95.

Porcu P, Mostallino MC, Sogliano C, Santoru F, Berretti R, Concas A. Long-term administration with levonorgestrel decreases allopregnanolone levels and alters GABA(A) receptor subunit expression and anxiety-like behavior. Pharmacol Biochem Behav. 2012 Aug;102(2):366-72.

Ciccarelli A, Calza A, Santoru F, Grasso F, Concas A, Sassoè-Pognetto M, Giustetto M.Morphine withdrawal produces erk-dependent and erk-independent epigenetic marks in neurons of the nucleus accumbens and lateral septum, Neuropharmacology, in press.