September 28 – October 3, 2014
2014.09.28
6.00 pm Registration
7.00 pm
Inaugural Lecture
Enzo Tramontano Summer School welcoming remarks
Giorgio Palù President of the European Society for Virology welcoming remarks
Carlo Federico Perno Introduction to Inaugural Lecture
Jan Balzarini Carbohydrate binding agents: novel therapeutic concept as selective antiviral compounds.
8.30 pm Dinner
2014.09.29
9.00 am
Plenary lectures
Chairman: Cristina Parolin
Stephan Becker Identifying targets for antifiloviral interventions
Maurizio Botta Design, synthesis and biological evaluation of human DDX3 inhibitors with multiple antiviral activities
11.00-11.15am Coffee break
11.15 am
Chairman: Stuart Le Grice
Eric Freed Development of potent and broadly active HIV-1 maturation inhibitors
Giorgio Palù Different approaches to develop effective antiviral strategies
1.00 pm Lunch
3.30-5.00 pm Discussion groups
5.00-6.00 pm Coffee break – Poster session I
6.00-7.15 pm
Student talks
Chairman: Elias Maccioni
Florencia Linero Isolation and characterization of Nanobodies against Junin virus as new and improved treatment option for Argentine hemorrhagic fever
Serena Massari Targeting Influenza A Virus RNA-dependent-RNA- polymerase: development of PA/PB1 interaction inhibitors
Finny Varghese Novel antivirals affecting Alphaviruses, including the re- emerging Chikungunya virus
Marta Cadeddu Identification and characterization of HERV-K (HML-10) in GRCh37/hg19 assembly and their possible association with the human diseases
Pouya Hassandavish Mechanism study of baicalein activity against dengue virus replication
8.00 pm Dinner
2014.09.30
9.00 am
Plenary lectures
Chairman: Giorgio Palù
Le Grice Stuart Therapeutic Targeting of the Retroviral RNA Genome
Mátyus Péter Through hardships to the drug candidate (Per aspera ad astra) – old and new concepts in HIV drug discovery
11.00-11.15am Coffee Break
11.15 am
Chairman: Eric Freed
Thomas Mertens Mechanisms, clinical problems and management of resistance against herpesvirus infections
Birgitta Wöhrl Inhibition of Foamy Virus RNase H by HIV-1 RNase H inhibitors development of a model system
1.00 pm Lunch
3.30-5.00 pm Discussion groups
5.00-6.00 pm Coffee break – Poster session II
6.00-7.15 pm
Student talks
Chairman: Maurizio Botta
St. Patrick Reid The lipid kinase sphingosine kinase 2 is an essential host factor recruited by Chikungunya virus during infection
Agharbaoui Fatima E From natural products to HIV-1 IN/LEDGF interaction inhibitors:computational and synthetic approaches
Michele Celestino Unrevealing the molecular mechanisms accounting for the FIV envelope glycoprotein ability to overcome feline tetherin restriction
Valeria Cannas Identification of VP35 dsRNA binding pocket useful residues for development of small-molecules inhibitors against Ebola virus
Łukasz Świątek Antiviral activity of leaves and cones of Alnus sieboldiana Matsum against HHV-1
8.00 pm Dinner
2014.10.01
9.00 am
Plenary lectures
Chairman: Jan Balzarini
Reuben Harris The Biological and Pathological Importance of Enzyme- Catalyzed DNA Cytosine Deamination
Federico Gago Structure-based computational strategies in the design of antiviral drugs
11.00-11.15am Coffee Break
11.15 am
Chairman: Thomas Mertens
Kvaratskhelia Mamuka Multimerization selective inhibitors of HIV-1 integrase
Enzo Tramontano Are human endogenous retroviruses possible drug targets?
1.00 pm Lunch
Free afternoon
8.00 pm Dinner
2014.10.02
9.00 am
Plenary lectures
Chairman: Stephan Becker
Ben Berkhout New anti-HIV approaches: peptide inhibitors, RNAi gene therapy and the humanized mouse model for drug testing
Maccioni Elias Drug design: principles and considerations
11.00-11.15am Coffee Break
11.15 am
Round table on “Working in a company after the PhD”
Chairman: Stuart Le Grice
Participant: Franco Lori and Vincenzo Summa
1.00 pm Lunch
3.00-4.30 pm Discussion groups
4.30-5.00 pm Coffee Break
5.00-7.00 pm
Plenary lectures
Chairman: Reuben Harris
Roberto Di Santo Inhibiting the HIV Integration Process: Past, Present, and the Future
Camarasa María José gp120 as a target of the design and discovery of HIV- entry/fusion inhibitors
8.00 pm Social Dinner
2014.10.03
Breakfast and leaving