Joanna Izabela Lachowicz

 

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2012-      PostDoc

2007-2010 PhD (DOTTORATO DI RICERCA)

Università degli Studi di Cagliari (Italy)
Dipartimento di Scienze Chimiche
Centro interdipartimentale per lo studio di metalli in medicina
Title of the thesi: Iron(III) and aluminum(III) complexes with hydroxypyrone and hydroxypyridinone derivatives aimed to design chelators with new perspectives.

 

2005-2006 Masters Degree (LAUREA SPECIALISTICA)
Uniwersytet Wroclawski (Poland)
Dipartment of Biotecnology
Title of the thesi: Coordination of copper ions by hexapeptides containing histidine residues

2002-2005 Bachelor Degree (LAUREA TRIENALE)

Uniwersytet Wroclawski (Poland)
Dipartment of Biotecnology
Title of the thesi: Superoxide dismutase activity of prion protein

 

PUBLICATIONS:

  1. Interaction between aspergillic acid and iron(III): A potentiometric, UV-Vis, 1H NMR and quantum chemical study.

Nurchi, Valeria M.; Crisponi, Guido; Pivetta, Tiziana; Tramontano, Enzo; Marincola, Flaminia Cesare; Lachowicz, Joanna I. Polyhedron (2009), 28(4), 763-768. DOI:10.1016/j.poly.2008.12.031.

  1. Effect of substituents on complex stability aimed at designing new iron(III) and aluminum(III) chelators

Nurchi, Valeria Marina; Pivetta, Tiziana; Lachowicz, Joanna Izabela; Crisponi, Guido Journal of Inorganic Biochemistry (2009), 103(2), 227-236. DOI:10.1016/j.jinorgbio.2008.10.011

  1. Iron(III) and aluminum(III) complexes with hydroxypyrone ligands aimed to design kojic acid derivatives with new perspectives.

Nurchi, Valeria Marina; Crisponi, Guido; Lachowicz, Joanna Izabela; Murgia, Sergio; Pivetta, Tiziana; Remelli, Maurizio; Rescigno, Antonio; Niclos-Gutierrez, Juan; Gonzalez-Perez, Josefa Maria; Dominguez-Martin, Alicia; Journal of Inorganic Biochemistry (2010), 104(5), 560-569. DOI:10.1016/j.jinorgbio.2010.01.007

  1. Nuovi derivati dell’acido kojico come chelanti per il ferro(III).

Joanna Lachowicz, La Chimica&L’industria. Vol 91, 109-11, 2009; ISSN:0009-4315

  1. Kojic acid derivatives as powerful chelators for iron(III) and aluminium(III).

Nurchi Valeria M; Lachowicz Joanna I; Crisponi Guido; Murgia Sergio; Arca Massimiliano; Pintus Anna; Gans Peter; Niclos-Gutierrez Juan; Dominguez-Martin Alicia; Castineiras Alfonso; Dalton transactions (Cambridge, England : 2003) (2011), 40(22), 5984-98.

  1. Different approaches to the study of chelating agents for iron and aluminium overload pathologies

Crisponi, Guido; Dean, Annalisa; Di Marco, Valerio; Lachowicz, Joanna I.; Nurchi, Valeria M.; Remelli, Maurizio; Tapparo, Andrea; Analytical and Bioanalytical Chemistry (2013), 405(2-3), 585-601. DOI:10.1007/s00216-012-6468-7

  1. Complex formation equilibria of CuII and ZnII with triethylenetetramine and its mono- and di-acetyl metabolites

Nurchi, Valeria M.; Crisponi, Guido; Crespo-Alonso, Miriam; Lachowicz, Joanna I.; Szewczuk, Zbigniew; Cooper, Garth J. S.; Dalton Transactions (2013), 42(17), 6161-6170. DOI:10.1039/c2dt32252h.

  1. The meaning of aluminium exposure on human health and aluminium-related diseases

Guido Crisponi , Daniela Fanni , Clara Gerosa , Sonia Nemolato , Valeria M. Nurchi , Miriam Crespo-Alonso , Joanna I. Lachowicz and Gavino Faa. BioMol Concepts 2013; 4(1): 77–87. DOI 10.1515/bmc-2012-0045.

  1. A family of hydroxypyrone ligands designed and synthesized as iron chelators.

Toso, Leonardo; Crisponi, Guido; Nurchi, Valeria M.; Crespo-Alonso, Miriam; Lachowicz, Joanna I.; Santos, M. Amelia; Marques, Sergio M.; Niclos-Gutierrez, Juan; Gonzalez-Perez, Josefa M.; Dominguez-Martin, Alicia; Journal of Inorganic Biochemistry (2013), 127, 220-231. DOI:10.1016/j.jinorgbio.2013.06.009.

 

  1. Hydroxypyrones, an intriguing family of chelating agents for Fe(III) and Al(III).

Leonardo Toso, Valeria M. Nurchi, Guido Crisponi, Miriam Crespo-Alonso, Joanna I. Lachowicz, Sergio M. Marques, Maria Amelia Santos, Juan Niclós-Gutiérrez, Alicia Domínguez-Martín, Josefa M. González-Pérez, Maria A. Zoroddu, Massimiliano Peana.

Contributo in congresso (Comunicazione), EUROBIC 11 (2012)  53-56, © los Autores, © Universidad de Granada, 02 May 2013 12:07, ISBN: 978-84-338-5418-6.

  1. Nickel Binding Sites in Histone Proteins: Spectroscopic and Structural Characterization.

M.A. Zoroddu, M. Peana, S. Medici, C. Solinas, J.I. Lachowicz, V.M. Nurchi, Contributo in congresso (Comunicazione), EUROBIC 11 (2012) 5-8, © los Autores, © Universidad de Granada, 02 May 2013 12:07, ISBN: 978-84-338-5418-6.

  1. State of art in chelating agents for the clinical treatment of metal poisoning.
  2. Crisponi, V.M. Nurchi, J.I. Lachowicz, M. Crespo-Alonso, L. Toso, M.A. Zoroddu

EUROBIC 11 (2012)  37-42, ISBN 978-88-7587-658-6

  1. IronIII and aluminiumIII complexes with substituted salicyl-aldehydes and salicylic acids.

Nurchi, Valeria M.; Crespo-Alonso, Miriam; Toso, Leonardo; Lachowicz, Joanna I.; Crisponi, Guido; Alberti, Giancarla; Biesuz, Raffaela; Dominguez-Martin, Alicia; Niclos-Gutierrez, Juan; Gonzalez-Perez, Josefa M.; Journal of Inorganic Biochemistry (2013), 128, 174-182. DOI:10.1016/j.jinorgbio.2013.07.016.

  1. Searching for new aluminum chelating agents: A family of hydroxypyrone ligands.

Toso, Leonardo; Crisponi, Guido; Nurchi, Valeria M.; Crespo-Alonso, Miriam; Lachowicz, Joanna I.; Mansoori, Delara; Arca, Massimiliano; Santos, M. Amelia; Marques, Sergio M.; Gano, Lurdes; Journal of Inorganic Biochemistry (2014), 130, 112-121. DOI:10.1016/j.jinorgbio.2013.09.022.

  1. Manganese and cobalt binding in a multi-histidinic fragment.

Peana, Massimiliano; Medici, Serenella; Nurchi, Valeria Marina; Crisponi, Guido; Lachowicz, Joanna Izabela; Zoroddu, Maria Antonietta; Dalton Transactions (2013), 42(46), 16293-16301. DOI:10.1039/c3dt51091c.

  1. Metal Ions in the Pathogenesis of Alzheimer’s Disease: An Open Field.

Guido Crisponi, Valeria M. Nurchi, Daniela Fanni, Clara Gerosa, Sonia Nemolato, Miriam Crespo-Alonso, Leonardo Toso, Joanna I. Lachowicz and Gavino Faa. Alzheimer Disorders. Atta-ur-Rahaman/Editor. Volume 1. Frontiers in Clinical Drug Research.Bentham eBooks. eISBN: 978-1-60805-722-1; ISBN: 978-1-60805-723-8; ISSN: 2214-5168.

  1. Chelation Therapy for Metal Intoxication: Comments from a Thermodynamic Viewpoint.

Nurchi, Valeria Marina; Crespo-Alonso, Miriam; Toso, Leonardo; Lachowicz, Joanna Izabela; Crisponi, Guido, Mini-Reviews in Medicinal Chemistry (2013), 13(11), 1541-1549. DOI:10.2174/13895575113139990077

  1. Kill or Cure: Misuse of chelation therapy for human.

Guido Crisponi, Valeria M. Nurchi, Joanna I. Lachowicz, Miriam Crespo-Alonso, Maria A. Zoroddu, Massimiliano Peana, Coordination Chemistry Reviews (2014), 284, 278-285, DOI: 10.1016/j.ccr.2014.04.023

  1. Nutritional iron deficiency: the role of oral iron supplementation.

Joanna I. Lachowicz, Valeria M. Nurchi, Daniela Fanni, Clara Gerosa, Massimiliano Peana, Maria A. Zoroddu, Current Medicinal Chemistry (2014) 21, 3775-3784

DOI: 10.2174/0929867321666140706143925

  1. Toxicity of Nanoparticles

Maria Antonietta Zoroddu, Serenella Medici, Alessia Ledda, Valeria Marina Nurchi, Joanna I. Lachowicz, Massimiliano Peana, Current Medicinal Chemistry (2014) 21, 3837-3853, WOS: 000343167000005

  1. Noble metals in medicine: latest advances.

Serenella Medici, Massimiliano Peana, Valeria Marina Nurchi, Joanna Izabela, Guido Crisponi, Maria Antonietta Zoroddu. Coordination Chemistry Reviews (2015) 284, 329-350, DOI: 10.1016/j.ccr.2014.08.002

  1. A bis-3-hydroxy-4-pyrone as a potential therapeutic iron chelating agent. Effect of connecting and side chains on the complex structures and metal ion selectivity.

Guido Crisponi, Valeria M. Nurchi, Massimiliano Arca, Miriam Crespo-Alonso, Joanna I.

Lachowicz, Delara Mansoori, Leonardo Toso, Giuseppina Pichiri, M. Amelia Santos, Sergio M.

Marques, Juan Niclós-Gutiérrez, Josefa M. González Pérez, Alicia Domínguez-Martín, Duane

Choquesillo-Lazarte, Zbigniew Szewczuk, M. Antonietta Zoroddu, Massimiliano Peana. Journal of Inorganic Biochemistry, Journal of Inorganic Bochemistry, 2014,

 

  1. Warns againts unapproved ‘chelation therapy’.

Guido Crisponi, Valeria M. Nurchi, Massimiliano Arca, Joanna I. Lachowicz, Miriam Crespo-Alonso, Antonietta Zoroddu, Massimiliano Peana. Journal of Biological Inorganic Chemistry (2014) 19, S711-S712. 12th European Biological Inorganic Chemistry Conference (EuroBIC) AUG24-28, 2014.

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