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TitoloData di pubblicazioneAutore(i)RivistaEditore
Response to Perspectives on the Classical Enzyme Carbonic Anhydrase and the Search for Inhibitors2021Angeli, Andrea; Carta, Fabrizio; Nocentini, Alessio; Winum, Jean-Yves; Zalubovskis, Raivis; Onnis..., Valentina; Eldehna, Wagdy M; Capasso, Clemente; Carradori, Simone; Donald, William A; Dedhar, Shoukat; Supuran, Claudiu TBIOPHYSICAL JOURNAL
Ruthenium(II) Complexes of Isothiazole Ligands: Crystal Structure, HSA/DNA Interactions, Cytotoxic Activity and Molecular Docking Simulations2020Djukić, Maja B.; Jeremić, Marija S.; Filipović, Ignjat P.; Klisurić, Olivera R.; Jelić, Ratomir M....; Popović, Suzana; Matić, Sanja; Onnis, Valentina; Matović, Zoran D.CHEMISTRYSELECT
2-(Arylamino)-6-(trifluoromethyl)nicotinic Acid Derivatives: New HIV-1 RT Dual Inhibitors Active on Viral Replication2020Corona, Angela; Onnis, Valentina; Del Vecchio, Claudia; Esposito, Francesca; Cheng, Yung-Chi; Tra...montano, EnzoMOLECULES
Synthesis and Biological Evaluation of 2-Substituted Benzyl-/Phenylethylamino-4-amino-5-aroylthiazoles as Apoptosis-Inducing Anticancer Agents2020Oliva, Paola; Onnis, Valentina; Balboni, Elisa; Hamel, Ernest; Estévez-Sarmiento, Francisco; Quin...tana, José; Estévez, Francisco; Brancale, Andrea; Ferla, Salvatore; Manfredini, Stefano; Romagnoli, RomeoMOLECULES
Exploring the fatty acid amide hydrolase and cyclooxygenase inhibitory properties of novel amide derivatives of ibuprofen2020Deplano, Alessandro; Karlsson, Jessica; Svensson, Mona; Moraca, Federica; Catalanotti, Bruno; Fow...ler, Christopher J.; Onnis, ValentinaJOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
Carbonic anhydrase inhibitors targeting metabolism and tumor microenvironment2020Angeli, Andrea; Carta, Fabrizio; Nocentini, Alessio; Winum, Jean-Yves; Zalubovskis, Raivis; Akdem...ir, Atilla; Onnis, Valentina; Eldehna, Wagdy M.; Capasso, Clemente; Simone, Giuseppina De; Monti, Simona Maria; Carradori, Simone; Donald, William A.; Dedhar, Shoukat; Supuran, Claudiu T.METABOLITES
In-Vitro Evaluation of Antioxidant, Antiproliferative and Photo-Protective Activities of Benzimidazolehydrazone Derivatives2020Baldisserotto, Anna; Demurtas, Monica; Lampronti, Ilaria; Tacchini, Massimo; Moi, Davide; Balboni..., Gianfranco; Vertuani, Silvia; Manfredini, Stefano; Onnis, ValentinaPHARMACEUTICALS
Appliance of the piperidinyl-hydrazidoureido linker to benzenesulfonamide compounds: Synthesis, in vitro and in silico evaluation of potent carbonic anhydrase II, IX and XII inhibitors2020Moi, Davide; Nocentini, Alessio; Deplano, Alessandro; Osman, Sameh M.; AlOthman, Zeid A.; Piras, ...Valentina; Balboni, Gianfranco; Supuran, Claudiu T.; Onnis, ValentinaBIOORGANIC CHEMISTRY
Synthesis and evaluation of antioxidant and antiproliferative activity of 2-arylbenzimidazoles2020Baldisserotto, Anna; Demurtas, Monica; Lampronti, Ilaria; Tacchini, Massimo; Moi, Davide; Balboni..., Gianfranco; Pacifico, Salvatore; Vertuani, Silvia; Manfredini, Stefano; Onnis, ValentinaBIOORGANIC CHEMISTRY
Sulfonamide/sulfamate switch with a series of piperazinylureido derivatives: Synthesis, kinetic and in silico evaluation as carbonic anhydrase isoforms I, II, IV, and IX inhibitors2020Nocentini, Alessio; Moi, Davide; Deplano, Alessandro; Osman, Sameh M.; AlOthman, Zeid A.; Balboni..., Gianfranco; Supuran, Claudiu T.; Onnis, ValentinaEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
The fatty acid amide hydrolase and cyclooxygenase-inhibitory properties of novel amide derivatives of carprofen2020Deplano, Alessandro; Karlsson, Jessica; Fowler, Christopher J.; Onnis, ValentinaBIOORGANIC CHEMISTRY
Indole derivatives as multifunctional drugs: Synthesis and evaluation of antioxidant, photoprotective and antiproliferative activity of indole hydrazones2019Demurtas, Monica; Baldisserotto, Anna; Lampronti, Ilaria; Moi, Davide; Balboni, Gianfranco; Pacif...ico, Salvatore; Vertuani, Silvia; Manfredini, Stefano; Onnis, ValentinaBIOORGANIC CHEMISTRY
Structure-activity relationship with pyrazoline-based aromatic sulfamates as carbonic anhydrase isoforms I, II, IX and XII inhibitors: Synthesis and biological evaluation2019Moi, Davide; Nocentini, Alessio; Deplano, Alessandro; Balboni, Gianfranco; Supuran, Claudiu T.; O...nnis, ValentinaEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Benzylamides and piperazinoarylamides of ibuprofen as fatty acid amide hydrolase inhibitors2019Deplano, Alessandro; Cipriano, Mariateresa; Moraca, Federica; Novellino, Ettore; Catalanotti, Bru...no; Fowler, Christopher J.; Onnis, ValentinaJOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
Targeting prokineticin system counteracts hypersensitivity, neuroinflammation, and tissue damage in a mouse model of bortezomib-induced peripheral neuropathy2019Moschetti, Giorgia; Amodeo, Giada; Maftei, Daniela; Lattanzi, Roberta; Procacci, Patrizia; Sartor...i, Patrizia; Balboni, Gianfranco; Onnis, Valentina; Conte, Vincenzo; Panerai, Alberto; Sacerdote, Paola; Franchi, SilviaJOURNAL OF NEUROINFLAMMATION
Synthesis and in vitro evaluation of piperazinyl-ureido sulfamates as steroid sulfatase inhibitors2019Moi, Davide; Foster, Paul A.; Rimmer, Lucy G.; Jaffri, Alisha; Deplano, Alessandro; Balboni, Gian...franco; Onnis, Valentina; Potter, Barry V. L.EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Discovery of thiazolin-4-one-based aromatic sulfamates as a new class of carbonic anhydrase isoforms I, II, IV, and IX inhibitors2018Nocentini, Alessio; Moi, Davide; Balboni, Gianfranco; Onnis, Valentina; Supuran, Claudiu T.BIOORGANIC CHEMISTRY
Benzofuran hydrazones as potential scaffold in the development of multifunctional drugs: Synthesis and evaluation of antioxidant, photoprotective and antiproliferative activity2018Baldisserotto, Anna; Demurtas, Monica; Lampronti, Ilaria; Moi, Davide; Balboni, Gianfranco; Vertu...ani, Silvia; Manfredini, Stefano; Onnis, ValentinaEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Synthesis and biological evaluation of novel pyrazoline-based aromatic sulfamates with potent carbonic anhydrase isoforms II, IV and IX inhibitory efficacy2018Nocentini, Alessio; Moi, Davide; Balboni, Gianfranco; Salvadori, Severo; Onnis, Valentina; Supura...n, Claudiu T.BIOORGANIC CHEMISTRY
3,4-Dihydroquinazoline derivatives inhibit the activities of cholinesterase enzymes2017Park, Byeongyeon; Nam, Ji Hye; Kim, Jin Han; Kim, Hyoung Ja; Onnis, Valentina; Balboni, Gianfranc...o; Lee, Kyung Tae; Park, Jeong Ho; Catto, Marco; Carotti, Angelo; Lee, Jae YeolBIOORGANIC & MEDICINAL CHEMISTRY LETTERSElsevier Ltd
Haloacetophenones as newly potent nematicides against Meloidogyne incognita2017Tocco, Graziella; Eloh, Kodjo; Onnis, Valentina; Sasanelli, Nicola; Caboni, PierluigiINDUSTRIAL CROPS AND PRODUCTS
Novel propanamides as fatty acid amide hydrolase inhibitors2017Deplano, Alessandro; Morgillo, Carmine Marco; Demurtas, Monica; Björklund, Emmelie; Cipriano, Mar...iateresa; Svensson, Mona; Hashemian, Sanaz; Smaldone, Giovanni; Pedone, Emilia; Luque, F. Javier; Cabiddu, MARIA GRAZIA; Novellino, Ettore; Fowler, Christopher J.; Catalanotti, Bruno; Onnis, ValentinaEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Design, synthesis and antiviral evaluation of novel heteroarylcarbothioamide derivatives as dual inhibitors of HIV-1 Reverse transcriptase-associated RNase H and RDDP functions2017Corona, Angela; Onnis, Valentina; Deplano, Alessandro; Bianco, Giulia; Demurtas, Monica; Distinto..., Simona; Cheng, Yung Chi; Alcaro, Stefano; Esposito, Francesca; Tramontano, EnzoPATHOGENS AND DISEASE
Antagonism of EG-VEGF receptors as targeted therapy for choriocarcinoma progression in vitro and in vivo2017Traboulsi, Wael; Sergent, Frederic; Boufettal, Houssine; Brouillet, Sophie; Slim, Rima; Hoffmann,... Pascale; Benlahfid, Mohammed; Zhou, qun yong; Balboni, Gianfranco; Onnis, Valentina; Bolze, Pierre Adrien; Salomon, Aude; Sauthier, Philippe; Mallet, François; Aboussaouira, Touria; Feige, Jean Jacques; Benharouga, Mohamed; Alfaidy, NadiaCLINICAL CANCER RESEARCH
Nematicidal activity of acetophenones and chalcones against Meloidogyne incognita and structure-activity considerations2016Caboni P; Aissani N; Demurtas M; Ntalli N; Onnis VPEST MANAGEMENT SCIENCE
Effect of the T-type channel blocker KYS-05090S in mouse models of acute and neuropathic pain2016M'Dahoma, Saïd; Gadotti, Vinicius M; Zhang, Fang Xiong; Park, Byeongyeon; Nam, Ji Hye; Onnis, Val...entina; Balboni, Gianfranco; Lee, Jae Yeol; Zamponi, Gerald W.PFLÜGERS ARCHIV
DESIGN, SYNTHESIS AND PHARMACOLOGICAL INVESTIGATION OF NEW DNA METHYLTRANSFERASE INHIBITORS2016Balboni, Gianfranco; Deplano, Alessandro; Demurtas, Monica; Arimondo, Paola B.; Masson, Veronique...; Onnis, Valentina
Discovery of a novel class of profen derivatives as FAAH inhibitors: MD and QM/MM studies of the binding mode and 3D SAR2016Morgillo, CM; Deplano, A; Karlsson, J; Cipriano, M; Björklund, E; Fowler, Cj; Onnis, V; Luque, Fj...; Catalanotti, B
Potent nematicidal activity of maleimide derivatives on Meloidogyne incognita2016Eloh, K; Demurtas, M; Mura, MG; Deplano, A; Onnis, V; Sasanelli, N; Maxia, A; Caboni, PJOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
Design, synthesis and evaluation of antiproliferative activity of new benzimidazolehydrazones2016Onnis, V; Demurtas, M; Deplano, A; Balboni, G; Baldisserotto, A; Manfredini, S; Pacifico, S; Liek...ens, S; Balzarini, JMOLECULES
Antagonism of the prokineticin system prevents and reverses allodynia and inflammation in a mouse model of diabetes2016Castelli, M; Amodeo, G; Negri, L; Lattanzi, R; Maftei, D; Gotti, C; Pistillo, F; Onnis, V; Congiu..., C; Panerai, AE; Sacerdote, P; Franchi, SPLOS ONE
Synthesis and carbonic anhydrase I, II, IX and XII inhibitory activity of sulfamates incorporating piperazinyl-ureido moieties2015Congiu, Cenzo; Onnis, Valentina; Deplano, Alessandro; Balboni, Gianfranco; Ceruso, Mariangela; Su...puran, Claudiu T.BIOORGANIC & MEDICINAL CHEMISTRY
In vitro nematicidal activity of aryl hydrazones and comparative GC-MS metabolomics analysis2015Eloh, K; Demurtas, M; Deplano, A; Ngoutane Mfopa, A; Murgia, A; Maxia, A; Onnis, V; Caboni, PJOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
Investigation of the mechanism of FAAH inhibition of profen amide derivatives2015Morgillo, CM; Deplano, A; Demurtas, M; Karlosson, J; Onnis, V; Congiu, C; Fowler, CJ; Catalanotti, B
Design, synthesis, and anti-HIV-1 activity of 1-substituted 3-(3,5-dimethylbenzyl)triazine derivatives2015Sakakibara, Norikazu; Balboni, Gianfranco; Congiu, Cenzo; Onnis, Valentina; Demizu, Yosuke; Misaw...a, Takashi; Kurihara, Masaaki; Kato, Yoshihisa; Maruyama, Tokumi; Toyama, Masaaki; Okamoto, Mika; Baba, MasanoriANTIVIRAL CHEMISTRY & CHEMOTHERAPY
Inhibitory effect of positively charged triazine antagonists of prokinecitin receptors on the transient receptor vanilloid type-1 (TRPV1) channel2015Petrocellis, Luciano De; Moriello, Aniello Schiano; Byun, Joon Seok; Sohn, Joo Mi; Lee, Jae Yeol;... Vázquez-Romero, Ana; Garrido, Maria; Messeguer, Angel; Zhang, Fang-Xiong; Zamponi, Gerald W; Deplano, Alessandro; Congiu, Cenzo; Onnis, Valentina; Balboni, Gianfranco; Marzo, Vincenzo DiPHARMACOLOGICAL RESEARCH
PPAR controls pregnancy outcome through activation of EG-VEGF: new insights into the mechanism of placental development2015Vanessa Garnier; Wael Traboulsi; Aude Salomon; Sophie Brouillet; Thierry Fournier; Carine Winkler...; Beatrice Desvergne; Pascale Hoffmann; Qun-Yong Zhou; Cenzo Congiu; Valentina Onnis; Mohamed Benharouga; Jean-Jacques Feige; Nadia AlfaidyAMERICAN JOURNAL OF PHYSIOLOGY: ENDOCRINOLOGY AND METABOLISM
TRPV1 modulators: synthesis and in vitro evaluation of 1-heteroarylpiperidinecarboxamide and piperazinylurea derivatives2015Congiu, C; Onnis, V; Balboni, G; Schiano-Moriello, A; Di Marzo, V; De Petrocellis, LEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Synthesis of sulfonamides incorporating piperazinyl-ureido moieties and their carbonic anhydrase I, II, IX and XII inhibitory activity2015Congiu, Cenzo; Onnis, Valentina; Deplano, Alessandro; Balboni, Gianfranco; Dedeoglu, Nurcan; Supu...ran, Claudiu T.BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Critical role for prokineticin 2 in CNS autoimmunity2015ABOU HAMDAN, M; Costanza, M; Fontana, E; DI DARIO, M; Musio, S; Congiu, Cenzo; Onnis, Valentina; ...Lattanzi, R; Radaelli, M; Martinelli, V; Salvadori, S; Negri, L; Poliani, Pl; Farina, C; Balboni, Gianfranco; Steinman, L; Pedotti, R.NEUROLOGY® NEUROIMMUNOLOGY & NEUROINFLAMMATION
Interaction of the N-(3-Methylpyridin-2-yl)amide derivatives of flurbiprofen and ibuprofen with FAAH: Enantiomeric selectivity and binding mode2015Karlsson, Jessica; Morgillo, Carmine M; Deplano, Alessandro; Smaldone, Giovanni; Pedone, Emilia; ...Luque, F. Javier; Svensson, Mona; Novellino, Ettore; Congiu, Cenzo; Onnis, Valentina; Catalanotti, Bruno; Fowler, Christopher J.PLOS ONE
Characterisation of (R)-2-(2-Fluorobiphenyl-4-yl)-N-(3-Methylpyridin-2-yl)Propanamide as a Dual Fatty Acid Amide Hydrolase: Cyclooxygenase Inhibitor2015Gouveia-Figueira, S; Karlsson, J; Deplano, A; Hashemian, S; Svensson, M; Fredriksson Sundbom, M; ...Congiu, C; Onnis, V; Fowler, CjPLOS ONE
Synthesis and carbonic anhydrase I, II, IX and XII inhibition studies of 4-N,N-disubstituted sulfanilamides incorporating 4,4,4-trifluoro-3-oxo-but-1-enyl, phenacylthiourea and imidazol-2(3H)-one/thione moieties2014Congiu C; ONNIS V; Balboni G; Supuran CTBIOORGANIC & MEDICINAL CHEMISTRY LETTERS
An important role for prokineticin 2 in autoimmune CNS demyelination2014Abou-hamdan M.; Costanza M.; Fontana E.; Musio S.; Di Dario M.; Congiu C.; Onnis V; Lattanzi R.; ...Negri L.; Poliani P.L.; Farina C.; Balboni G.; Steinman L.; Pedotti R.JOURNAL OF NEUROIMMUNOLOGY
Interaction and reactivity of synthetic aminoisoflavones with metal-free and metalassociated amyloid-beta2014DeToma AS; Krishnamoorthy J; Nam Y; Lee HJ; Brender JR; Kochi A; Lee D; Onnis V; Congiu C; Manfre...dini S; Vertuani S; Balboni G; Ramamoorthy A; Lim MHCHEMICAL SCIENCE
Design, synthesis and pharmacological investigation on new FAAH inhibitors2014Onnis V; Congiu C; Deplano A; Demurtas M; Cipriano M; Fowler C.J; Morgillo C.M; Catalanotti BCHEMMEDCHEM
Design, Synthesis and Evaluation of new 2-(Arylidenehydrazino)pyrrole Derivatives as Potential Antitumor Agents2014Congiu C; Onnis V; Deplano A; Demurtas M; Balboni GCHEMMEDCHEM
A new convenient synthetic method and preliminary pharmacological characterization of triazinediones as prokineticin receptor antagonists2014Congiu C; Onnis V; Deplano A; Salvadori S; Marconi V; Maftei D; Negri L; Lattanzi R; Balboni GEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Halogenated triazinediones behave as antagonists of PKR1: in vitro and in vivo pharmacological characterization2014Lattanzi, R; Congiu, Cenzo; Onnis, Valentina; Deplano, Alessandro; Salvadori, S; Marconi, V; Maft...ei, D; Francioso, A; Ambrosio, C; Casella, I; Costa, T; Caltabiano, G; Matsoukas M., T; Balboni, Gianfranco; Negri, L.INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH
Inhibition of fatty acid amide hydrolase and cyclooxygenase by the N-(3-methylpyridin-2-yl)amide derivatives of flurbiprofen and naproxen2013Cipriano M.; Björklund E.; Wilson A.A.; Congiu C.; Onnis V; Fowler C.J.EUROPEAN JOURNAL OF PHARMACOLOGY
   
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