| Titolo | Data di pubblicazione | Autori | Tipo | Abstract |
|---|
| Targeting prokineticin system counteracts hypersensitivity, neuroinflammation, and tissue damage in a mouse model of bortezomib-induced peripheral neuropathy | 2019 | Moschetti, Giorgia; Amodeo, Giada; Maftei, Daniela; Lattanzi, Roberta; Procacci, Patrizia; Sartori, Patrizia; BALBONI, GIANFRANCO ; ONNIS, VALENTINA ; Conte, Vincenzo; Panerai, Alberto; Sacerdote, Paola; Franchi, Silvia | 1 Contributo su Rivista::1.1 Articolo in rivista | |
| Indole derivatives as multifunctional drugs: Synthesis and evaluation of antioxidant, photoprotective and antiproliferative activity of indole hydrazones | 2019 | DEMURTAS, MONICA ; Baldisserotto, Anna; Lampronti, Ilaria; MOI, DAVIDE ; BALBONI, GIANFRANCO ; Pacifico, Salvatore; Vertuani, Silvia; Manfredini, Stefano; ONNIS, VALENTINA | 1 Contributo su Rivista::1.1 Articolo in rivista | |
| Benzylamides and piperazinoarylamides of ibuprofen as fatty acid amide hydrolase inhibitors | 2019 | DEPLANO, ALESSANDRO ; Cipriano, Mariateresa; Moraca, Federica; Novellino, Ettore; Catalanotti, Bruno; Fowler, Christopher J.; ONNIS, VALENTINA | 1 Contributo su Rivista::1.1 Articolo in rivista | |
| Synthesis and evaluation of antioxidant and antiproliferative activity of 2-arylbenzimidazoles | 2019 | Baldisserotto, Anna; DEMURTAS, MONICA ; Lampronti, Ilaria; Tacchini, Massimo; MOI, DAVIDE ; BALBONI, GIANFRANCO ; Pacifico, Salvatore; Vertuani, Silvia; Manfredini, Stefano; ONNIS, VALENTINA | 1 Contributo su Rivista::1.1 Articolo in rivista | |
| Sulfonamide/sulfamate switch with a series of piperazinylureido derivatives: Synthesis, kinetic and in silico evaluation as carbonic anhydrase isoforms I, II, IV, and IX inhibitors | 2019 | Nocentini, Alessio; MOI, DAVIDE ; DEPLANO, ALESSANDRO ; Osman, Sameh M.; AlOthman, Zeid A.; BALBONI, GIANFRANCO ; Supuran, Claudiu T.; ONNIS, VALENTINA | 1 Contributo su Rivista::1.1 Articolo in rivista | |
| Structure-activity relationship with pyrazoline-based aromatic sulfamates as carbonic anhydrase isoforms I, II, IX and XII inhibitors: Synthesis and biological evaluation | 2019 | MOI, DAVIDE ; Nocentini, Alessio; DEPLANO, ALESSANDRO ; BALBONI, GIANFRANCO ; Supuran, Claudiu T.; ONNIS, VALENTINA | 1 Contributo su Rivista::1.1 Articolo in rivista | |
| Synthesis and in vitro evaluation of piperazinyl-ureido sulfamates as steroid sulfatase inhibitors | 2019 | MOI, DAVIDE ; Foster, Paul A.; Rimmer, Lucy G.; Jaffri, Alisha; DEPLANO, ALESSANDRO ; BALBONI, GIANFRANCO ; ONNIS, VALENTINA ; Potter, Barry V. L. | 1 Contributo su Rivista::1.1 Articolo in rivista | |
| Discovery of thiazolin-4-one-based aromatic sulfamates as a new class of carbonic anhydrase isoforms I, II, IV, and IX inhibitors | 2018 | Nocentini, Alessio; MOI, DAVIDE ; BALBONI, GIANFRANCO ; ONNIS, VALENTINA ; Supuran, Claudiu T. | 1 Contributo su Rivista::1.1 Articolo in rivista | |
| Benzofuran hydrazones as potential scaffold in the development of multifunctional drugs: Synthesis and evaluation of antioxidant, photoprotective and antiproliferative activity | 2018 | Baldisserotto, Anna; DEMURTAS, MONICA ; Lampronti, Ilaria; MOI, DAVIDE ; BALBONI, GIANFRANCO ; Vertuani, Silvia; Manfredini, Stefano; ONNIS, VALENTINA | 1 Contributo su Rivista::1.1 Articolo in rivista | |
| Synthesis and biological evaluation of novel pyrazoline-based aromatic sulfamates with potent carbonic anhydrase isoforms II, IV and IX inhibitory efficacy | 2018 | Nocentini, Alessio; MOI, DAVIDE ; BALBONI, GIANFRANCO ; Salvadori, Severo; ONNIS, VALENTINA ; Supuran, Claudiu T. | 1 Contributo su Rivista::1.1 Articolo in rivista | |
| Novel propanamides as fatty acid amide hydrolase inhibitors | 2017 | DEPLANO, ALESSANDRO ; Morgillo, Carmine Marco; DEMURTAS, MONICA ; Björklund, Emmelie; Cipriano, Mariateresa; Svensson, Mona; Hashemian, Sanaz; Smaldone, Giovanni; Pedone, Emilia; Luque, F. Javier; CABIDDU, MARIA GRAZIA ; Novellino, Ettore; Fowler, Christopher J.; Catalanotti, Bruno; ONNIS, VALENTINA | 1 Contributo su Rivista::1.1 Articolo in rivista | |
| Design, synthesis and antiviral evaluation of novel heteroarylcarbothioamide derivatives as dual inhibitors of HIV-1 Reverse transcriptase-associated RNase H and RDDP functions | 2017 | CORONA, ANGELA ; ONNIS, VALENTINA ; DEPLANO, ALESSANDRO ; BIANCO, GIULIA ; DEMURTAS, MONICA ; DISTINTO, SIMONA ; Cheng, Yung Chi; Alcaro, Stefano; ESPOSITO, FRANCESCA ; TRAMONTANO, ENZO | 1 Contributo su Rivista::1.1 Articolo in rivista | |
| Antagonism of EG-VEGF receptors as targeted therapy for choriocarcinoma progression in vitro and in vivo | 2017 | Traboulsi, Wael; Sergent, Frederic; Boufettal, Houssine; Brouillet, Sophie; Slim, Rima; Hoffmann, Pascale; Benlahfid, Mohammed; Zhou, qun yong; BALBONI, GIANFRANCO ; ONNIS, VALENTINA ; Bolze, Pierre Adrien; Salomon, Aude; Sauthier, Philippe; Mallet, François; Aboussaouira, Touria; Feige, Jean Jacques; Benharouga, Mohamed; Alfaidy, Nadia | 1 Contributo su Rivista::1.1 Articolo in rivista | |
| Haloacetophenones as newly potent nematicides against Meloidogyne incognita | 2017 | TOCCO, GRAZIELLA ; ELOH, KODJO ; ONNIS, VALENTINA ; Sasanelli, Nicola; CABONI, PIERLUIGI | 1 Contributo su Rivista::1.1 Articolo in rivista | |
| 3,4-Dihydroquinazoline derivatives inhibit the activities of cholinesterase enzymes | 2017 | Park, Byeongyeon; Nam, Ji Hye; Kim, Jin Han; Kim, Hyoung Ja; ONNIS, VALENTINA ; BALBONI, GIANFRANCO ; Lee, Kyung Tae; Park, Jeong Ho; Catto, Marco; Carotti, Angelo; Lee, Jae Yeol | 1 Contributo su Rivista::1.1 Articolo in rivista | |
| Nematicidal activity of acetophenones and chalcones against Meloidogyne incognita and structure-activity considerations | 2016 | CABONI, PIERLUIGI ; AISSANI, NADHEM ; DEMURTAS, MONICA ; NTALLI, NIKOLETTA ; ONNIS, VALENTINA | 1 Contributo su Rivista::1.1 Articolo in rivista | |
| Potent nematicidal activity of maleimide derivatives on Meloidogyne incognita | 2016 | ELOH, KODJO ; DEMURTAS, MONICA ; MURA, MANUEL GIACOMO ; DEPLANO, ALESSANDRO ; ONNIS, VALENTINA ; Sasanelli, N; MAXIA, ANDREA ; CABONI, PIERLUIGI | 1 Contributo su Rivista::1.1 Articolo in rivista | |
| Design, synthesis and evaluation of antiproliferative activity of new benzimidazolehydrazones | 2016 | ONNIS, VALENTINA ; DEMURTAS, MONICA ; DEPLANO, ALESSANDRO ; BALBONI, GIANFRANCO ; Baldisserotto, A; Manfredini, S; Pacifico, S; Liekens, S; Balzarini, J. | 1 Contributo su Rivista::1.1 Articolo in rivista | |
| Effect of the T-type channel blocker KYS-05090S in mouse models of acute and neuropathic pain | 2016 | M'Dahoma, Saïd; Gadotti, Vinicius M; Zhang, Fang Xiong; Park, Byeongyeon; Nam, Ji Hye; ONNIS, VALENTINA ; BALBONI, GIANFRANCO ; Lee, Jae Yeol; Zamponi, Gerald W. | 1 Contributo su Rivista::1.1 Articolo in rivista | |
| Antagonism of the prokineticin system prevents and reverses allodynia and inflammation in a mouse model of diabetes | 2016 | Castelli, M; Amodeo, G; Negri, L; Lattanzi, R; Maftei, D; Gotti, C; Pistillo, F; ONNIS, VALENTINA ; CONGIU, CENZO ; Panerai, AE; Sacerdote, P; Franchi, S. | 1 Contributo su Rivista::1.1 Articolo in rivista | |
| DESIGN, SYNTHESIS AND PHARMACOLOGICAL INVESTIGATION OF NEW DNA METHYLTRANSFERASE INHIBITORS | 2016 | BALBONI, GIANFRANCO ; DEPLANO, ALESSANDRO ; DEMURTAS, MONICA ; Arimondo, Paola B.; Masson, Veronique; ONNIS, VALENTINA | 4 Contributo in Atti di Convegno (Proceeding)::4.1 Contributo in Atti di convegno | - |
| DIHYDROQUINAZOLINE BENZYLAMIDES AS ACETYLCHOLINESTERASE AND BUTYRYLCHOLINESTERASE INHIBITORS | 2016 | ONNIS, VALENTINA; BALBONI, GIANFRANCO ; DEPLANO, ALESSANDRO ; DEMURTAS, MONICA ; Buyn, Joon Seok; Sohn, Joo Mi; Lee, Jae Yeol; Catto, Marco; Pisani, Leonardo; Carotti, Angelo | 4 Contributo in Atti di Convegno (Proceeding)::4.1 Contributo in Atti di convegno | - |
| Discovery of a novel class of profen derivatives as FAAH inhibitors: MD and QM/MM studies of the binding mode and 3D SAR | 2016 | Morgillo, CM; DEPLANO, ALESSANDRO ; Karlsson, J; Cipriano, M; Björklund, E; Fowler, Cj; ONNIS, VALENTINA; Luque, Fj; Catalanotti, B. | 4 Contributo in Atti di Convegno (Proceeding)::4.1 Contributo in Atti di convegno | - |
| In vitro nematicidal activity of aryl hydrazones and comparative GC-MS metabolomics analysis | 2015 | ELOH, KODJO ; DEMURTAS, MONICA ; DEPLANO, ALESSANDRO ; Ngoutane Mfopa, A; MURGIA, ANTONIO ; MAXIA, ANDREA ; ONNIS, VALENTINA ; CABONI, PIERLUIGI | 1 Contributo su Rivista::1.1 Articolo in rivista | |
| Synthesis and carbonic anhydrase I, II, IX and XII inhibitory activity of sulfamates incorporating piperazinyl-ureido moieties | 2015 | CONGIU, CENZO ; ONNIS, VALENTINA ; DEPLANO, ALESSANDRO ; BALBONI, GIANFRANCO ; Ceruso, Mariangela; Supuran, Claudiu T. | 1 Contributo su Rivista::1.1 Articolo in rivista | |
| Critical role for prokineticin 2 in CNS autoimmunity | 2015 | ABOU HAMDAN M; COSTANZA M; FONTANA E; DI DARIO M; MUSIO S; CONGIU, CENZO ; ONNIS, VALENTINA ; LATTANZI R; RADAELLI M; MARTINELLI V; SALVADORI S; NEGRI L; POLIANI PL; FARINA C; BALBONI, GIANFRANCO ; STEINMAN L; PEDOTTI R. | 1 Contributo su Rivista::1.1 Articolo in rivista | |
| TRPV1 modulators: synthesis and in vitro evaluation of 1-heteroarylpiperidinecarboxamide and piperazinylurea derivatives | 2015 | CONGIU, CENZO ; ONNIS, VALENTINA ; BALBONI, GIANFRANCO ; Schiano Moriello, A; Di Marzo, V; De Petrocellis, L. | 1 Contributo su Rivista::1.1 Articolo in rivista | |
| PPAR controls pregnancy outcome through activation of EG-VEGF: new insights into the mechanism of placental development | 2015 | Vanessa Garnier; Wael Traboulsi; Aude Salomon; Sophie Brouillet; Thierry Fournier; Carine Winkler; Beatrice Desvergne; Pascale Hoffmann; Qun Yong Zhou; CONGIU, CENZO ; ONNIS, VALENTINA ; Mohamed Benharouga; Jean Jacques Feige; Nadia Alfaidy | 1 Contributo su Rivista::1.1 Articolo in rivista | |
| Synthesis of sulfonamides incorporating piperazinyl-ureido moieties and their carbonic anhydrase I, II, IX and XII inhibitory activity | 2015 | CONGIU, CENZO ; ONNIS, VALENTINA ; DEPLANO, ALESSANDRO ; BALBONI, GIANFRANCO ; Dedeoglu, Nurcan; Supuran, Claudiu T. | 1 Contributo su Rivista::1.1 Articolo in rivista | |
| Inhibitory effect of positively charged triazine antagonists of prokinecitin receptors on the transient receptor vanilloid type-1 (TRPV1) channel | 2015 | Petrocellis, Luciano De; Moriello, Aniello Schiano; Byun, Joon Seok; Sohn, Joo Mi; Lee, Jae Yeol; Vázquez Romero, Ana; Garrido, Maria; Messeguer, Angel; Zhang, Fang Xiong; Zamponi, Gerald W; DEPLANO, ALESSANDRO ; CONGIU, CENZO ; ONNIS, VALENTINA ; BALBONI, GIANFRANCO ; Marzo, Vincenzo Di | 1 Contributo su Rivista::1.1 Articolo in rivista | |
| Design, synthesis, and anti-HIV-1 activity of 1-substituted 3-(3,5-dimethylbenzyl)triazine derivatives | 2015 | Sakakibara, Norikazu; BALBONI, GIANFRANCO ; CONGIU, CENZO ; ONNIS, VALENTINA ; Demizu, Yosuke; Misawa, Takashi; Kurihara, Masaaki; Kato, Yoshihisa; Maruyama, Tokumi; Toyama, Masaaki; Okamoto, Mika; Baba, Masanori | 1 Contributo su Rivista::1.1 Articolo in rivista | |
| Interaction of the N-(3-Methylpyridin-2-yl)amide derivatives of flurbiprofen and ibuprofen with FAAH: Enantiomeric selectivity and binding mode | 2015 | Karlsson, Jessica; Morgillo, Carmine M; DEPLANO, ALESSANDRO ; Smaldone, Giovanni; Pedone, Emilia; Luque, F. Javier; Svensson, Mona; Novellino, Ettore; CONGIU, CENZO ; ONNIS, VALENTINA ; Catalanotti, Bruno; Fowler, Christopher J. | 1 Contributo su Rivista::1.1 Articolo in rivista | |
| Characterisation of (R)-2-(2-Fluorobiphenyl-4-yl)-N-(3-Methylpyridin-2-yl)Propanamide as a Dual Fatty Acid Amide Hydrolase: Cyclooxygenase Inhibitor | 2015 | Gouveia Figueira, S; Karlsson, J; DEPLANO, ALESSANDRO ; Hashemian, S; Svensson, M; Fredriksson Sundbom, M; CONGIU, CENZO ; ONNIS, VALENTINA ; Fowler, Cj | 1 Contributo su Rivista::1.1 Articolo in rivista | |
| Dihydroquinazoline and Triazinedione Derivatives as Prok1 and Prok2 receptor antagonists in HEK-293 transfected cells | 2015 | BALBONI, GIANFRANCO ; CONGIU, CENZO ; DEPLANO, ALESSANDRO ; DEMURTAS, MONICA ; Buyn, Joon Seok; Sohn, Joo Mi; Lee, Jae Yeol; Sbai, Oualid; Rondard, Philippe; ONNIS, VALENTINA | 4 Contributo in Atti di Convegno (Proceeding)::4.1 Contributo in Atti di convegno | |
| Investigation of the mechanism of FAAH inhibition of profen amide derivatives | 2015 | Morgillo, CM; DEPLANO, ALESSANDRO ; DEMURTAS, MONICA ; Karlosson, J; ONNIS, VALENTINA; CONGIU, CENZO ; Fowler, CJ; Catalanotti, B. | 4 Contributo in Atti di Convegno (Proceeding)::4.1 Contributo in Atti di convegno | - |
| Synthesis and SIRT1 modulation studies of amides and hydrazides of benzoic acid incorporating a (2-trifluoromethylpyridin-4-yl)amino moiety | 2015 | CONGIU, CENZO ; BALBONI, GIANFRANCO ; ONNIS, VALENTINA | 4 Contributo in Atti di Convegno (Proceeding)::4.1 Contributo in Atti di convegno | - |
| Design, synthesis and pharmacological investigation on new FAAH inhibitors | 2014 | ONNIS, VALENTINA ; CONGIU, CENZO ; DEPLANO, ALESSANDRO ; DEMURTAS, MONICA ; Cipriano M; Fowler C. J; Morgillo C. M; Catalanotti B. | 1 Contributo su Rivista::1.5 Abstract in rivista | - |
| Design, Synthesis and Evaluation of new 2-(Arylidenehydrazino)pyrrole Derivatives as Potential Antitumor Agents | 2014 | CONGIU, CENZO ; ONNIS, VALENTINA ; DEPLANO, ALESSANDRO ; DEMURTAS, MONICA ; BALBONI, GIANFRANCO | 1 Contributo su Rivista::1.5 Abstract in rivista | - |
| Interaction and reactivity of synthetic aminoisoflavones with metal-free and metalassociated amyloid-beta | 2014 | DeToma AS; Krishnamoorthy J; Nam Y; Lee HJ; Brender JR; Kochi A; Lee D; ONNIS, VALENTINA ; CONGIU, CENZO ; Manfredini S; Vertuani S; BALBONI, GIANFRANCO ; Ramamoorthy A; Lim MH | 1 Contributo su Rivista::1.1 Articolo in rivista | |
| Synthesis and carbonic anhydrase I, II, IX and XII inhibition studies of 4-N,N-disubstituted sulfanilamides incorporating 4,4,4-trifluoro-3-oxo-but-1-enyl, phenacylthiourea and imidazol-2(3H)-one/thione moieties | 2014 | CONGIU, CENZO ; ONNIS, VALENTINA ; BALBONI, GIANFRANCO ; Supuran CT | 1 Contributo su Rivista::1.1 Articolo in rivista | |
| An important role for prokineticin 2 in autoimmune CNS demyelination | 2014 | Abou hamdan M.; Costanza M.; Fontana E.; Musio S.; Di Dario M.; CONGIU, CENZO ; ONNIS, VALENTINA ; Lattanzi R.; Negri L.; Poliani P. L.; Farina C.; BALBONI, GIANFRANCO ; Steinman L.; Pedotti R. | 1 Contributo su Rivista::1.5 Abstract in rivista | |
| A new convenient synthetic method and preliminary pharmacological characterization of triazinediones as prokineticin receptor antagonists | 2014 | CONGIU, CENZO ; ONNIS, VALENTINA ; DEPLANO, ALESSANDRO ; Salvadori S; Marconi V; Maftei D; Negri L; Lattanzi R; BALBONI, GIANFRANCO | 1 Contributo su Rivista::1.1 Articolo in rivista | |
| Halogenated triazinediones behave as antagonists of PKR1: in vitro and in vivo pharmacological characterization | 2014 | Lattanzi R; CONGIU, CENZO ; ONNIS, VALENTINA ; DEPLANO, ALESSANDRO ; Salvadori S; Marconi V; Maftei D; Francioso A; Ambrosio C; Casella I; Costa T; Caltabiano G; Matsoukas M. T; BALBONI, GIANFRANCO ; Negri L. | 1 Contributo su Rivista::1.1 Articolo in rivista | |
| Inhibition of fatty acid amide hydrolase and cyclooxygenase by the N-(3-methylpyridin-2-yl)amide derivatives of flurbiprofen and naproxen | 2013 | Cipriano M.; Björklund E.; Wilson A. A.; CONGIU, CENZO ; ONNIS, VALENTINA ; Fowler C. J. | 1 Contributo su Rivista::1.1 Articolo in rivista | |
| Inhibitory properties of ibuprofen and its amide analogues towards the hydrolysis and cyclooxygenation of the endocannabinoid anandamide | 2013 | Fowler CJ; Björklund E; Lichtman AH; Naidu PS; CONGIU, CENZO ; ONNIS, VALENTINA | 1 Contributo su Rivista::1.1 Articolo in rivista | |
| Synthesis and biological evaluation of novel acylhydrazone derivatives as potential antitumor agents | 2013 | CONGIU, CENZO ; ONNIS, VALENTINA | 1 Contributo su Rivista::1.1 Articolo in rivista | |
| DESIGN, SYNTHESIS, AND EVALUATION OF (ISO)NIPECOTAMIDE AND
PIPERAZINYLUREA DERIVATIVES AS TRPV1 MODULATORS | 2013 | CONGIU, CENZO ; ONNIS, VALENTINA; Schiano Moriello A; Di Marzo V.; De Petrocellis L. | 4 Contributo in Atti di Convegno (Proceeding)::4.1 Contributo in Atti di convegno | - |
| N-(2-HYDROXYARYL)AMIDES ENDOWED WITH ANTIPROLIFERATIVE
ACTIVITY | 2013 | ONNIS, VALENTINA; CONGIU, CENZO | 4 Contributo in Atti di Convegno (Proceeding)::4.1 Contributo in Atti di convegno | - |
| Novel 2-amino-isoflavones exhibit aryl hydrocarbon receptor agonist or antagonist activity in a species/cell-specific context | 2012 | Wall RJ; He G; Denison MS; CONGIU, CENZO ; ONNIS, VALENTINA ; Fernandes A; Bell DR; Rose M; Rowlands JC; BALBONI, GIANFRANCO ; Mellor I.R. | 1 Contributo su Rivista::1.1 Articolo in rivista | |
| Flavones and structurally related 4-chromenones inhibit carbonic anhydrases by a different mechanism of action compared to coumarins | 2012 | BALBONI, GIANFRANCO ; CONGIU, CENZO ; ONNIS, VALENTINA ; Maresca A; Scozzafava A; Winum JY; Maietti A; Supuran CT | 1 Contributo su Rivista::1.1 Articolo in rivista | |
