{"id":1879,"date":"2013-10-25T22:22:52","date_gmt":"2013-10-25T22:22:52","guid":{"rendered":"http:\/\/people.unica.it\/molecularmedicine\/?page_id=1879"},"modified":"2023-06-20T08:24:34","modified_gmt":"2023-06-20T08:24:34","slug":"luigi-atzori","status":"publish","type":"page","link":"https:\/\/people.unica.it\/molecularmedicine\/faculty\/nutritional-and-metabolic-sciences\/luigi-atzori\/","title":{"rendered":"Luigi Atzori"},"content":{"rendered":"

Department of Biomedical Sciences\"DSC_0061\"<\/span><\/a><\/span><\/p>\n

Telephone: +39 0706758390<\/span><\/p>\n

Mobile: +39 3355481487<\/span><\/p>\n

E-mail:<\/span> latzori@unica.it<\/span><\/a><\/span><\/span><\/p>\n

Personal webpage:<\/span> here<\/a><\/span><\/span><\/p>\n

Main areas of expertise: Clinical metabolomics; Pathological chemistry<\/span><\/p>\n

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\u2666 Advances in Metabolomics<\/span><\/span><\/p>\n

Since 2008, metabolomics one of the youngest \u201c-omics\u201d has been the major interest of Atzori group. By using these tool, and collaborating with different clinicians such as neonatologists, neurologists, cardiologists, oncologists, forensic doctors, we are trying to better understand the metabolic changes in biofluids and tissues for identifying new biomarkers of diseases, predict the prognosis and the response to the therapy. A better understanding of the role of metabolites changes in physiophatological conditions might lead to a new tailored medicine. Main pathological conditions under investigations are: neonatal hypoxia, multiple sclerosis, epilepsy, amyotrophic lateral sclerosis, heart failure, time from death, cancer, chronic inflammatory bowel disease. To address these, we are developing analytical chemistry techniques, by using  NMR spectroscopy and mass spectrometry, and innovative statistical approaches. The working environment includes medical doctors, biologists, chemists, pharmaceutical chemists and mathematicians. The Atzori group is also involved in the designing of database tools for metabolomics.<\/span><\/p>\n

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Key publications:<\/span><\/p>\n

Scano P, Locci E, Noto A, Navarra G, Murgia F, Lussu M, Barberini L, Atzori L, DeGiorgio F, Rosa F, D\u2019Aloja E (2013) 1H-NMR Metabolite fingerprinting as a new tool for body fluid identification in forensic science. Magn Reson Chem<\/i> 51<\/b>: 454-462<\/span><\/p>\n

Syggelou A, Iacovidou N, Atzori L, Xanthos T, Fanos V (2012) Metabolomics in the developing human being. Pediatr Clin North Am <\/i>59<\/b>: 1039-1058<\/span><\/p>\n

Griffin JL, Atherton H, Shockcor J, Atzori L (2011) Metabolomics as a tool for cardiac research. Nat Rev Cardiol <\/i>8<\/b>: 630-643<\/span><\/p>\n

Atzori L, Mussap M, Noto A, Barberini L, Puddu M, Irmesi R, Murgia F, Lussu M, Fanos V (2011) Clinical metabolomics and urinary NGAL for the early prediction of chronic kidney disease in healthy adults born ELBW. J Matern Fetal Neonatal Med <\/i>24 <\/b>(Suppl 2): 41-44<\/span><\/p>\n

Atzori L, <\/b>Antonucci R, Barberini L, Locci E, Marincola FC, Scano P, Cortesi P, Agostiniani R, Defraia R, Weljie A, Gazzolo D, Lai A, Fanos V (2011) 1H NMR-based metabolomic analysis of urine from preterm and term neonates. Front Biosci<\/i> (Elite Ed.) 3<\/b>: 1005-1012<\/span><\/p>\n

Atzori L, Antonucci R, Barberini L, Locci E, Cesare Marincola F, Scano P, Cortesi P, Agostiniani R, Weljie A, Lai A, Fanos V (2010) 1H NMR-based metabolic profiling of urine from children with nephrouropathies. Front Biosci<\/i> (Elite Ed.) 2<\/b>: 725-732<\/span><\/p>\n

Atzori L, Xanthos T, Barberini L, Aantonucci R, Murgia F, Lussu M, Aroni F, Varsami M, Papalois A, Lai A, D\u2019Aloja E, Iacovidou N, Fanos V (2010) A metabolomic approach in an experimental model of hypoxia-reoxygenation in newborn piglets: urine predicts outcome. J Maternal Fetal Neonatal Med <\/i>23<\/b> (Suppl. 3): 134-137<\/span><\/p>\n

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\"nrcardio.2011.138-f2\"<\/span><\/a><\/span><\/p>\n

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From Griffin et al. , Nat Rev Cardiol <\/em>8<\/b>: <\/em>630-643, 2011. Modified with permission obtained from Nature Publishing Group \u00a9,  Last RL et al.,  Nat Mol Cell Biol<\/em> 8<\/strong>: 167-174, 2007<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

Department of Biomedical Sciences Telephone: +39 0706758390 Mobile: +39 3355481487 E-mail: latzori@unica.it Personal webpage: here Main areas of expertise: Clinical metabolomics; Pathological chemistry     \u2666 Advances in Metabolomics Since 2008, metabolomics one of the youngest \u201c-omics\u201d has been the major interest of Atzori group. By using these tool, and collaborating with different clinicians such as neonatologists, neurologists, cardiologists, oncologists, forensic doctors, we are trying to better understand the metabolic changes in biofluids and tissues for identifying new biomarkers of diseases, predict the prognosis and the response to the therapy. A better understanding of the role of metabolites changes in […]<\/a><\/p>\n","protected":false},"author":2009,"featured_media":0,"parent":1656,"menu_order":2,"comment_status":"closed","ping_status":"closed","template":"","meta":{"ngg_post_thumbnail":0,"footnotes":""},"class_list":["post-1879","page","type-page","status-publish","hentry","post-seq-1","post-parity-odd","meta-position-corners","fix"],"_links":{"self":[{"href":"https:\/\/people.unica.it\/molecularmedicine\/wp-json\/wp\/v2\/pages\/1879","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/people.unica.it\/molecularmedicine\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/people.unica.it\/molecularmedicine\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/people.unica.it\/molecularmedicine\/wp-json\/wp\/v2\/users\/2009"}],"replies":[{"embeddable":true,"href":"https:\/\/people.unica.it\/molecularmedicine\/wp-json\/wp\/v2\/comments?post=1879"}],"version-history":[{"count":23,"href":"https:\/\/people.unica.it\/molecularmedicine\/wp-json\/wp\/v2\/pages\/1879\/revisions"}],"predecessor-version":[{"id":3433,"href":"https:\/\/people.unica.it\/molecularmedicine\/wp-json\/wp\/v2\/pages\/1879\/revisions\/3433"}],"up":[{"embeddable":true,"href":"https:\/\/people.unica.it\/molecularmedicine\/wp-json\/wp\/v2\/pages\/1656"}],"wp:attachment":[{"href":"https:\/\/people.unica.it\/molecularmedicine\/wp-json\/wp\/v2\/media?parent=1879"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}