{"id":1668,"date":"2013-10-17T10:35:10","date_gmt":"2013-10-17T10:35:10","guid":{"rendered":"http:\/\/people.unica.it\/molecularmedicine\/?page_id=1668"},"modified":"2023-06-20T08:22:25","modified_gmt":"2023-06-20T08:22:25","slug":"roberta-loddo","status":"publish","type":"page","link":"https:\/\/people.unica.it\/molecularmedicine\/faculty\/molecular-oncology-and-pathology\/roberta-loddo\/","title":{"rendered":"Roberta Loddo"},"content":{"rendered":"<p style=\"text-align: justify\"><span style=\"color: #000000\">Department of Biomedical Sciences<a href=\"http:\/\/people.unica.it\/molecularmedicine\/files\/2013\/10\/Loddo.png\"><span style=\"color: #000000\"><img decoding=\"async\" class=\" wp-image-2261 alignright\" src=\"http:\/\/people.unica.it\/molecularmedicine\/files\/2013\/10\/Loddo-274x300.png\" alt=\"Loddo\" width=\"173\" height=\"189\" srcset=\"https:\/\/people.unica.it\/molecularmedicine\/files\/2013\/10\/Loddo-274x300.png 274w, https:\/\/people.unica.it\/molecularmedicine\/files\/2013\/10\/Loddo-2x2.png 2w, https:\/\/people.unica.it\/molecularmedicine\/files\/2013\/10\/Loddo.png 316w\" sizes=\"(max-width: 173px) 100vw, 173px\" \/><\/span><\/a><\/span><\/p>\n<p style=\"text-align: justify\"><span style=\"color: #000000\">Telephone: &nbsp;+39&nbsp;0706754202<\/span><\/p>\n<p style=\"text-align: justify\"><span style=\"color: #000000\">Fax: +39&nbsp;0706754210<\/span><\/p>\n<p style=\"text-align: justify\"><span style=\"color: #000000\">E-mail:<\/span>&nbsp;<span style=\"text-decoration: underline\"><span style=\"color: #0000ff\"><a style=\"color: #0000ff;text-decoration: underline\" href=\"mailto:rloddo@unica.it\">rloddo@unica.it<\/a><\/span><\/span><\/p>\n<p><span style=\"color: #000000\">Personal webpage:<\/span> <a href=\"https:\/\/www.unica.it\/unica\/it\/ateneo_s07_ss01.page?contentId=SHD30451\">here<\/a><\/p>\n<p><span style=\"color: #000000\">Main areas of expertise: Virology; Drug discovery<\/span><\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<hr>\n<p>\u2666&nbsp;<span style=\"text-decoration: underline;color: #000000\">Virology and drug discovery<\/span><\/p>\n<p style=\"text-align: justify\"><span style=\"color: #000000\">The research topics are the discovery of antiviral and antiproliferative agents. In particular, the activities mainly focused on design and validation of molecules with antiviral activity, including identification of their molecular targets, study of mechanisms of action and characterization of genotypic and phenotypic drug-resistant mutants.<\/span><\/p>\n<hr>\n<p><span style=\"color: #000000\">Key publications:<\/span><\/p>\n<p style=\"text-align: justify\"><span style=\"color: #000000\">Spallarossa A, Rotolo C, Sissi C, Marson G, Greco ML, Ranise A,&nbsp;La Colla&nbsp;P,&nbsp;Busonera B,&nbsp;Loddo&nbsp;R (2013)&nbsp;Further SAR studies on bicyclic basic merbarone analogues as potent antiproliferative agents.&nbsp;<em>Bioorg &amp; Med Chem<\/em>&nbsp;<strong>21<\/strong>: 6328-6336<\/span><\/p>\n<p style=\"text-align: justify\"><span style=\"color: #000000\">Caron M, Besson G, Etenna SL, Mintsa-Ndong A, Mourtas S, Radaelli A, Morghen CD,&nbsp;Loddo&nbsp;R,&nbsp;La Colla P, Antimisiaris SG, Kazanji M&nbsp;(2010)&nbsp;Protective properties of non-nucleoside reverse transcriptase inhibitor (MC1220) incorporated into liposome against intravaginal challenge of Rhesus Macaques with RT-SHIV.&nbsp;<em>Virology<\/em>&nbsp;<strong>405<\/strong>: 225-233<\/span><\/p>\n<p style=\"text-align: justify\"><span style=\"color: #000000\">Tonelli M, Vazzana I, Tasso B, Boido V, Sparatore F, Fermeglia M, Paneni MS, Posocco P, Pricl S,&nbsp;La Colla P,&nbsp;Ibba C, Secci B, Collu G, &nbsp;Loddo&nbsp;R (2009)&nbsp;Antiviral and cytotoxic activities of aminoarylazo compounds and aryltriazene derivatives.&nbsp;<em>Bioorg &amp; Med Chem<\/em>&nbsp;<strong>17<\/strong>: 4425-444<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Department of Biomedical Sciences Telephone: &nbsp;+39&nbsp;0706754202 Fax: +39&nbsp;0706754210 E-mail:&nbsp;rloddo@unica.it Personal webpage: here Main areas of expertise: Virology; Drug discovery &nbsp; &nbsp; \u2666&nbsp;Virology and drug discovery The research topics are the discovery of antiviral and antiproliferative agents. In particular, the activities mainly focused on design and validation of molecules with antiviral activity, including identification of their molecular targets, study of mechanisms of action and characterization of genotypic and phenotypic drug-resistant mutants. Key publications: Spallarossa A, Rotolo C, Sissi C, Marson G, Greco ML, Ranise A,&nbsp;La Colla&nbsp;P,&nbsp;Busonera B,&nbsp;Loddo&nbsp;R (2013)&nbsp;Further SAR studies on bicyclic basic merbarone analogues as potent antiproliferative agents.&nbsp;Bioorg &amp; Med <a href='https:\/\/people.unica.it\/molecularmedicine\/faculty\/molecular-oncology-and-pathology\/roberta-loddo\/' class='excerpt-more'>[&#8230;]<\/a><\/p>\n","protected":false},"author":2009,"featured_media":0,"parent":1658,"menu_order":6,"comment_status":"closed","ping_status":"closed","template":"","meta":{"ngg_post_thumbnail":0,"footnotes":""},"class_list":["post-1668","page","type-page","status-publish","hentry","post-seq-1","post-parity-odd","meta-position-corners","fix"],"_links":{"self":[{"href":"https:\/\/people.unica.it\/molecularmedicine\/wp-json\/wp\/v2\/pages\/1668","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/people.unica.it\/molecularmedicine\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/people.unica.it\/molecularmedicine\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/people.unica.it\/molecularmedicine\/wp-json\/wp\/v2\/users\/2009"}],"replies":[{"embeddable":true,"href":"https:\/\/people.unica.it\/molecularmedicine\/wp-json\/wp\/v2\/comments?post=1668"}],"version-history":[{"count":16,"href":"https:\/\/people.unica.it\/molecularmedicine\/wp-json\/wp\/v2\/pages\/1668\/revisions"}],"predecessor-version":[{"id":3422,"href":"https:\/\/people.unica.it\/molecularmedicine\/wp-json\/wp\/v2\/pages\/1668\/revisions\/3422"}],"up":[{"embeddable":true,"href":"https:\/\/people.unica.it\/molecularmedicine\/wp-json\/wp\/v2\/pages\/1658"}],"wp:attachment":[{"href":"https:\/\/people.unica.it\/molecularmedicine\/wp-json\/wp\/v2\/media?parent=1668"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}