|Titolo:||Lymphoma risk in animal breeders|
|Data di pubblicazione:||2011|
|Abstract:||Introduction. Occupational contact with breeding animals might be implicated in lymphoma etiology. Methods. In 1998-2003, 2337 incident lymphoma cases and 2434 controls participated in the EPILYMPH case-control study in six European countries. A detailed occupational history was collected in cases and controls, including species of breeding animals, their approximate number, and circumstances of contact. We conducted a preliminary analysis on ever exposed to contact with breeding animals, and we stratified the analysis by age at first exposure, whether before or after age 12. The Odds ratio (OR) and its 95% confidence interval (95% CI) was calculated with unconditional logistic regression for all lymphomas, and its major subtypes, adjusting by age, gender, and education. Results. Lymphoma risk (all subtypes combined) did not increase among exposed to contact with breeding animals (OR = 1.0, 95% CI 0.8 -1.2). Risk of DLBCL was significantly lower among subjects employed in poultry farms (OR = 0.6, 95% CI0.4 -1.0). This inverse association was observed among subjects who starter exposure before or at age 12 (OR = 0.5, 95% CI 0.2 -1.1), but not later. Conclusion. Early occupational contact with poultry might be associated with a decrease in risk of specific lymphoma subtypes.|
|Tipologia:||4.2 Abstract in Atti di convegno|
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