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Titolo: Modulation of 6-hydroxydopamine oxidation by various proteins
Autori: 
Data di pubblicazione: 1997
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BIOCHEMICAL PHARMACOLOGY  
Abstract: The spontaneous autoxidation of the neurotoxin 6-hydroxydopamine proceeds by a free radical chain reaction involving the superoxide anion radical and produces the corresponding chromogen 6-hydroxydopamine quinone and hydrogen peroxide. The rate of this reaction is increased in the presence of ceruloplasmin and peroxidase, and reduced by superoxide dismutase, catalase, and DT-diaphorase. We report some explanations of why these proteins may increase or reduce the rate of autoxidation of 6-hydroxydopamine. (C) 1997 Elsevier Science Inc.
Handle: http://hdl.handle.net/11584/100184
Tipologia:1.1 Articolo in rivista

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