Prodotti della ricerca
UNICA IRIS Institutional Research Information System
IRIS è il sistema di gestione integrata dei dati della ricerca (persone, progetti, pubblicazioni, attività) adottato dall'Università degli Studi di Cagliari dal mese di luglio 2015.

Titolo | Data di pubblicazione | Autore(i) | Rivista | Editore |
---|---|---|---|---|
2-methoxynaphthalen thiazole derivate : a new HIV-1 RT Ribonuclease H/DNA polymerase dual inhibitor active on viral replication | 2014 | Corona A; Meleddu R.; Esposito E.; Distinto S.; Bianco G.; Maccioni E. and Tramontano E.. | ||
Synthesis of different series of small molecules targeting HIV-1 RT, Candida albicans, MAO and G-Quadruplex | 11-apr-2013 | Università degli Studi di Cagliari | ||
2-(2-cycloalkylidene hydrazin-1-yl)-4-aryl-1,3-thiazoles: a promising class of antifungal agents | 2013 | Arridu A.; Meleddu R.; Bianco G.; Distinto S.; De Logu A.; Matyus P.; Maccioni E | ||
A novel series of 3,4-disubstituted dihydropyrazoles: Synthesis and evaluation for MAO enzyme inhibition | 2013 | Cardia, MARIA CRISTINA; Sanna, MARIA LUISA; Meleddu, Rita; Distinto, Simona; Yañez, M.; Viña, D.;... Lamela, M.; Maccioni, Elias | JOURNAL OF HETEROCYCLIC CHEMISTRY | |
Molecular Aspects of the RT/drug Interactions. Perspective of Dual Inhibitors | 2013 | Distinto S; Maccioni E; Meleddu R; Corona A; Alcaro S; Tramontano E | CURRENT PHARMACEUTICAL DESIGN | |
Design, Synthesis and Biological Evaluation of New 1,3-Diarylpropenones as Dual Inhibitors of HIV-1 RT. | 2013 | Esposito F; Meleddu R; Cannas V; Distinto S; Del Vecchio C; Biano G; Corona A; Cottiglia F; Alcar...o S; Parolin C; Maccioni E; Tramontano E. | ||
Design, Synthesis and Biological Evaluation of New 1,3-Diarylpropenones as Single Site Dual Inhibitors of HIV-1 RT | 2013 | Esposito F; Meleddu R; Cannas V; Distinto S; Del Vecchio C; Bianco G; Corona A; Cottiglia F; Alca...ro S; Parolin C; Maccioni E; Tramontano E | VIROLOGIE | |
Synthesis and biological activity evaluation of new dual-inhibitors of both associated functions of HIV-1 RT | 2013 | Meleddu R.; Distinto S.; Corona A.; Bianco G.; Arridu A.; Cannas V.; Tramontano E.; Alcaro S.; Ma...tyus P.; Maccioni E | ||
Site directed mutagenesis studies on HIV-1 reverse transcriptase (RT) shed light on the mechanism of action of a new Ribonuclease H/ DNA polymerase RT dual inhibitor | 2013 | Corona, Angela; Meleddu, Rita; Esposito, Francesca; Distinto, Simona; Bianco, Giulia; Maccioni, E...lias; Le Grice, S.; Tramontano, Enzo | RETROVIROLOGY | BioMed Central Ltd |
Synthesis and biological assessment of novel 2-thiazolylhydrazones and computational analysis of their recognition by monoamine oxidase B | 2012 | Distinto, Simona; Yáñez, M; Alcaro, S; Cardia, MARIA CRISTINA; Gaspari, M; Sanna, MARIA LUISA; Me...leddu, Rita; Ortuso, F; Kirchmair, J; Markt, P; Bolasco, A; Wolber, G; Secci, D; Maccioni, Elias | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | |
Mutagenic study on HIV-1 reverse transcriptase to explore the mechanism of action of HIV-1 reverse transcriptase dual inhibitors | 2012 | Corona A.; Meleddu R.; Esposito F.; Sanna M. L.; Distinto S.; Maccioni E; Tramontano E. | ||
SITE DIRECT MUTAGENESIS AND KINETIC STUDIES TO EXPLORE THE MECHANISM OF ACTION OF ISATIN DERIVATIVES AS HIV-1 REVERSE TRANSCRIPTASE DUAL INHIBITORS | 2012 | A. Corona; R. Meleddu; Esposito F; S. Distinto; E.Maccioni; S. Le Griceand E. Tramontano | ||
Synthesis and biological evaluation of new dual inhibitors of HIV-1 associated functions | 2012 | Tramontano E.; Meleddu R.; Corona A.; Distinto S.; Esposito F.; Cannas V.; Alcaro S.; Costa G.; O...rtuso F.; Maccioni E | ||
From classic to innovative approaches in HIV-1 infection treatment | 2012 | Maccioni E; Distinto S.; Alcaro S.; Meleddu R.; Esposito F.; Corona A.; Sanna M. L.; Tramontano E. | ||
3-Acetyl-2,5-diaryl-2,3-dihydro-1,3,4-oxadiazoles: A new scaffold for the selective inhibition of monoamine oxidase B | 2011 | Maccioni, Elias; Alcaro, S.; Cirilli, R.; Vigo, S.; Cardia, MARIA CRISTINA; Sanna, MARIA LUISA; M...eleddu, Rita; Yanez, M.; Costa, G.; Casu, Laura; Matyus, P.; Distinto, Simona | JOURNAL OF MEDICINAL CHEMISTRY | |
Design and synthesis of new isatin derivatives as HIV-1 reverse transcriptase associated ribonuclease H inhibitors | 2011 | F. Esposito; R. Meleddu; M.L. Sanna; S. Distinto; A. Corona; V. Cannas; E. Tramontano; M.C. Cardia | ANTIVIRAL RESEARCH | |
New promising scaffolds for the inhibition of monoamine oxidase B | 2011 | Sanna M. L.; Meleddu R.; Cardia M.C.; Distinto S.; Alcaro S.; Maccioni E | ||
Semicarbazide-sensitive amine oxidase/vascular adhesion protein-1: a patent survey | 2011 | Dunkel, P; Balogh, B; Meleddu, Rita; Maccioni, Elias; Gyires, K; Mátyus, P. | EXPERT OPINION ON THERAPEUTIC PATENTS | |
Design, synthesis and biolgical activity evaluation of new HIV-1 reverse transcriptase dual inhibitors | 2011 | Meleddu R; Corona A; Sanna M L; Esposito F; Cardia M C; Tramontano E; Maccioni E | ||
Isatin derivatives as new scaffolds for HIV-1 reverse transcriptase associated RNase H and RDDP dual inhibitors | 2011 | Corona A.; Meleddu R.; Esposito F.; Sanna M. L.; Distinto S; Maccioni E.; Tramontano E. |