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Titolo: New cycloalkylpyrazoles as potential cyclooxygenase inhibitors
Data di pubblicazione: 1998
Abstract: In this study some cycloalkyl-3-(N-substituted carbamoyl)-1-phenylpyrazoles have been synthesized in order to screen their capability to inhibit human cyclooxygenase. The synthetic pathway is based on the well known property of nitrilimines to undergo 1,3-dipolar cycloaddition reactions. The structures of all the synthesized compounds have been elucidated by means of both analytical and spectroscopic methods. (C) 1998 Elsevier Science S.A. All rights reserved.
Tipologia:1.1 Articolo in rivista

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