Prodotti della ricerca
| Titolo: | Evidence that nigral GABA mediates behavioural responses elicited by striatal dopamine receptor stimulation. |
| Autori: | |
| Data di pubblicazione: | 1978 |
| Rivista: | |
| Abstract: | Bilateral intranigral administration of GABA-receptor blockers (picrotoxin or bicuculline) elicits catatonia not surmountable by administration of apomorphine, a dopamine (DA)-receptor agonist. Unilateral intranigral administration of GABA-receptor blockers ipsilateral to a lesion of nigro-striatal DA-neurons induced with 60H-DA, antagonizes the contralateral turning produced by apomorphine. The results indicate that behaviouralresponseselicited by striatal DA-receptorstimulation are effected through a GABA-mediated inhibition of pars reticulata neurons. |
| Handle: | http://hdl.handle.net/11584/103724 |
| Tipologia: | 1.1 Articolo in rivista |
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