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IRIS è il sistema di gestione integrata dei dati della ricerca (persone, progetti, pubblicazioni, attività) adottato dall'Università degli Studi di Cagliari dal mese di luglio 2015.

Mostra risultati da 41 a 60 di 127
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TitoloData di pubblicazioneAutore(i)RivistaEditore
Identification and characterization of new DNA G-quadruplex binders selected by a combination of ligand and structure based virtual screening approaches2013Alcaro, S.; Musetti, C.; Distinto, S.; Casatti, M.; Zagotto, G.; Artese, A.; Parrotta, L.; Moraca..., F.; Costa, G.; Ortuso, F.; Maccioni, E.; Sissi, C.JOURNAL OF MEDICINAL CHEMISTRY
Toward the design of new DNA G-quadruplex ligands through rational analysis of polymorphism and binding data2013Artese, A; Costa, G; Distinto, S; Moraca, F; Ortuso, F; Parrotta, L; Alcaro, SEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
A novel series of 3,4-disubstituted dihydropyrazoles: Synthesis and evaluation for MAO enzyme inhibition2013Cardia, MARIA CRISTINA; Sanna, MARIA LUISA; Meleddu, Rita; Distinto, Simona; Yañez, M.; Viña, D.;... Lamela, M.; Maccioni, EliasJOURNAL OF HETEROCYCLIC CHEMISTRY
New dual inhibitors of RT associated functions: investigation on their mechanism and mode of action2013Distinto S.; Bianco G.; Meleddu R.; Cannas C.; Del Vecchio C.; Cottiglia F.; Alcaro S.; Parolin C....; Tramontano E.; Maccioni E
Investigation on the mechanism of action of new dual inhibitors of HIV-1 RT2013Bianco G; Distinto S.; Meleddu R.; Cannas C.; Del Vecchio C.; Cottiglia F.; Alcaro S.; Parolin C....; Tramontano E.; Maccioni E.
Molecular Aspects of the RT/drug Interactions. Perspective of Dual Inhibitors2013Distinto S; Maccioni E; Meleddu R; Corona A; Alcaro S; Tramontano ECURRENT PHARMACEUTICAL DESIGN
In search of new antitumor agents through the combination of individually active moieties: construction of a [3,5-diaryl-(4,5- dihydropyrazol-1-yl)-4-oxo-1,3-thiazol-5-ylidene]- 1H-indol-2-ones library2013Arridu A.; Meleddu R.; Bianco G; Distinto S; Bogdan D.; Matyus P.; Maccioni E.
Design, Synthesis and Biological Evaluation of New 1,3-Diarylpropenones as Dual Inhibitors of HIV-1 RT.2013Esposito F; Meleddu R; Cannas V; Distinto S; Del Vecchio C; Biano G; Corona A; Cottiglia F; Alcar...o S; Parolin C; Maccioni E; Tramontano E.
Design, Synthesis and Biological Evaluation of New 1,3-Diarylpropenones as Single Site Dual Inhibitors of HIV-1 RT2013Esposito F; Meleddu R; Cannas V; Distinto S; Del Vecchio C; Bianco G; Corona A; Cottiglia F; Alca...ro S; Parolin C; Maccioni E; Tramontano EVIROLOGIE
Synthesis and biological activity evaluation of new dual-inhibitors of both associated functions of HIV-1 RT2013Meleddu R.; Distinto S.; Corona A.; Bianco G.; Arridu A.; Cannas V.; Tramontano E.; Alcaro S.; Ma...tyus P.; Maccioni E
Site directed mutagenesis studies on HIV-1 reverse transcriptase (RT) shed light on the mechanism of action of a new Ribonuclease H/ DNA polymerase RT dual inhibitor2013Corona, Angela; Meleddu, Rita; Esposito, Francesca; Distinto, Simona; Bianco, Giulia; Maccioni, E...lias; Le Grice, S.; Tramontano, EnzoRETROVIROLOGYBioMed Central Ltd
Identification of HIV-1 reverse transcriptase dual inhibitors by a combined shape-, 2D-fingerprint- and pharmacophore-based virtual screening approach2012Distinto, Simona; Esposito, Francesca; Kirchmair, J; Cardia, MARIA CRISTINA; Gaspari, M; Maccioni..., Elias; Alcaro, S; Markt, P; Wolber, G; Zinzula, Luca; Tramontano, EnzoEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
The polymorphisms of DNA G-quadruplex investigated by docking experiments with telomestatin enantiomers2012Alcaro, S.; Costa, G.; Distinto, S; Moraca, F.; Ortuso, F.; Parrotta, L.; Artese, A.CURRENT PHARMACEUTICAL DESIGN
Design, synthesis and biological evaluation of new fluorenone derivatives as DNA G-quadruplex binders2012Alcaro S.; Maccioni E; Distinto S.; Parrotta L.; Meleddu R.; Artese A.; Moraca F.; Musetti C.; Si...ssi C.
The polymorfisms of DNA G-quadruplex investigated by docking experiments with Telomestatin enantiomers2012Alcaro S.; Costa G.; Distinto S; Moraca F.; Ortuso F.; Parrotta L. Artese A.
Synthesis and biological assessment of novel 2-thiazolylhydrazones and computational analysis of their recognition by monoamine oxidase B2012Distinto, Simona; Yáñez, M; Alcaro, S; Cardia, MARIA CRISTINA; Gaspari, M; Sanna, MARIA LUISA; Me...leddu, Rita; Ortuso, F; Kirchmair, J; Markt, P; Bolasco, A; Wolber, G; Secci, D; Maccioni, EliasEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
9-fluorenones as new scaffolds for G-quadruplex DNA2012Meleddu R.; Distinto S.; Parrotta L.; Maccioni E; Musetti C.; Sissi C; Sanna M. L.; Alcaro S.
The discovery of new G-quadruplex binders through a structure-based virtual screening approach 2012Moraca F.; Alcaro S.; Artese A.; Costa G.; Distinto S; Parrotta L.; Ortuso F.
GRID-based three-dimensional pharmacophores II: PharmBench, a benchmark data set for evaluating pharmacophore elucidation methods2012Cross, S.; Ortuso, F.; Baroni, M.; Costa, G.; Distinto, Simona; Moraca, F.; Alcaro, S.; Cruciani, G.JOURNAL OF CHEMICAL INFORMATION AND MODELING
Mutagenic study on HIV-1 reverse transcriptase to explore the mechanism of action of HIV-1 reverse transcriptase dual inhibitors2012Corona A.; Meleddu R.; Esposito F.; Sanna M. L.; Distinto S.; Maccioni E; Tramontano E.
   
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