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IRIS è il sistema di gestione integrata dei dati della ricerca (persone, progetti, pubblicazioni, attività) adottato dall'Università degli Studi di Cagliari dal mese di luglio 2015.

Mostra risultati da 21 a 40 di 123
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TitoloData di pubblicazioneAutoriTipoAbstract
Hit Identification of a Novel Dual Binder for h-telo/c-myc G-Quadruplex by a Combination of Pharmacophore Structure-Based Virtual Screening and Docking Refinement2016MACCIONI, ELIAS  ; DISTINTO, SIMONA  ; 1 Contributo su Rivista::1.1 Articolo in rivista
Sennoside A, derived from the traditional chinese medicine plant Rheum L., is a new dual HIV-1 inhibitor effective on HIV-1 replication2016ESPOSITO, FRANCESCA  ; CORONA, ANGELA  ; GRANDI, NICOLE  ; PIANO, DARIO  ; MACCIONI, ELIAS  ; DISTINTO, SIMONA  ; TRAMONTANO, ENZO  1 Contributo su Rivista::1.1 Articolo in rivista
New 4-[(3-cyclohexyl-4-aryl-2,3-dihydro-1,3-thiazol-2-ylidene)amino]benzene-1-sulfonamides, synthesis and inhibitory activity toward carbonic anhydrase I, II, IX, XII2015MELEDDU, RITA  ; MACCIONI, ELIAS  ; DISTINTO, SIMONA  ; BIANCO, GIULIA  ; MELIS, CLAUDIA  ; COTTIGLIA, FILIPPO  ; 1 Contributo su Rivista::1.1 Articolo in rivista
Methoxyflavones from Stachys glutinosa with binding affinity to opioid receptors: in silico, in vitro, and in vivo studies2015FLORIS, COSTANTINO  ; CABONI, PIERLUIGI  ; MACCIONI, ELIAS  ; DISTINTO, SIMONA  ; COTTIGLIA, FILIPPO  1 Contributo su Rivista::1.1 Articolo in rivista
(3Z)-3-(2-[4-(aryl)-1,3-thiazol-2-yl]hydrazin-1-ylidene)-2,3-dihydro- 1H -indol-2-one derivatives as dual inhibitors of HIV-1 reverse transcriptase2015MELEDDU, RITA  ; DISTINTO, SIMONA  ; CORONA, ANGELA  ; BIANCO, GIULIA  ; CANNAS, VALERIA  ; ESPOSITO, FRANCESCA  ; COTTIGLIA, FILIPPO  ; TRAMONTANO, ENZO  ; MACCIONI, ELIAS  1 Contributo su Rivista::1.1 Articolo in rivista
Structure-based virtual screening of novel natural alkaloid derivatives as potential binders of h-telo and c-myc DNA G-quadruplex conformations2015DISTINTO, SIMONA  ; MACCIONI, ELIAS  ; 1 Contributo su Rivista::1.1 Articolo in rivista
Design, synthesis, and biological evaluation of 1,3-diarylpropenones as dual inhibitors of HIV-1 reverse transcriptase2014MELEDDU, RITA  ; CANNAS, VALERIA  ; DISTINTO, SIMONA  ; SARAIS, GIORGIA  ; ESPOSITO, FRANCESCA  ; CORONA, ANGELA  ; COTTIGLIA, FILIPPO  ; MACCIONI, ELIAS  ; TRAMONTANO, ENZO  1 Contributo su Rivista::1.1 Articolo in rivista
2-methoxynaphthalen thiazole derivate : a new HIV-1 RT Ribonuclease H/DNA polymerase dual inhibitor active on viral replication2014CORONA, ANGELA  ; DISTINTO, SIMONA  ; 4 Contributo in Atti di Convegno (Proceeding)::4.3 Poster-
Site directed mutagenesis studies on HIV-1 reverse transcriptase (RT) enlighten the mechanism of action of a new Ribonuclease H/DNA polymerase RT dual inhibitor2014ESPOSITO, FRANCESCA  ; CORONA, ANGELA  ; DISTINTO, SIMONA  ; MACCIONI, ELIAS  ; 4 Contributo in Atti di Convegno (Proceeding)::4.3 Poster
N-Alkyl dien- and trienamides from the roots of Otanthus maritimus with binding affinity for opioid and cannabinoid receptors2013ANZANI, NICOLA  ; FLORIS, COSTANTINO  ; CABONI, PIERLUIGI  ; MACCIONI, ELIAS  ; DISTINTO, SIMONA  ; COTTIGLIA, FILIPPO  1 Contributo su Rivista::1.1 Articolo in rivista
Towards the total block of HIV-1 Reverse Transcriptase: the dual-inhibitors approach2013BIANCO, GIULIA  ; TRAMONTANO, ENZO  ; DISTINTO, SIMONA  ; MACCIONI, ELIAS  4 Contributo in Atti di Convegno (Proceeding)::4.3 Poster-
In search of new antitumor agents through the combination of individually active moieties: construction of a [3,5-diaryl-(4,5- dihydropyrazol-1-yl)-4-oxo-1,3-thiazol-5-ylidene]- 1H-indol-2-ones library2013BIANCO, GIULIA  ; DISTINTO, SIMONA  ; MACCIONI, ELIAS  4 Contributo in Atti di Convegno (Proceeding)::4.3 Poster-
Site directed mutagenesis studies on HIV-1 reverse transcriptase (RT) shed light on the mechanism of action of a new Ribonuclease H/ DNA polymerase RT dual inhibitor2013CORONA, ANGELA  ; MELEDDU, RITA  ; ESPOSITO, FRANCESCA  ; DISTINTO, SIMONA  ; BIANCO, GIULIA  ; MACCIONI, ELIAS  ; TRAMONTANO, ENZO  4 Contributo in Atti di Convegno (Proceeding)::4.2 Abstract in Atti di convegno-
MD protocol validation for the study of MAOB-inhibitor complexes2013BIANCO, GIULIA  ; DISTINTO, SIMONA  ; MACCIONI, ELIAS  4 Contributo in Atti di Convegno (Proceeding)::4.3 Poster-
2-(2-cycloalkylidene hydrazin-1-yl)-4-aryl-1,3-thiazoles: a promising class of antifungal agents2013BIANCO, GIULIA  ; DISTINTO, SIMONA  ; DE LOGU, ALESSANDRO  ; MACCIONI, ELIAS  4 Contributo in Atti di Convegno (Proceeding)::4.3 Poster-
Design, synthesis and biological activity evaluation of c-myc proto-oncogene binders as potential antitumor agents2013DISTINTO, SIMONA  ; BIANCO, GIULIA  ; MACCIONI, ELIAS  4 Contributo in Atti di Convegno (Proceeding)::4.3 Poster-
Molecular Aspects of the RT/drug Interactions. Perspective of Dual Inhibitors2013DISTINTO, SIMONA  ; MACCIONI, ELIAS  ; MELEDDU, RITA  ; CORONA, ANGELA  ; TRAMONTANO, ENZO  1 Contributo su Rivista::1.1 Articolo in rivista
Synthesis and biological activity evaluation of new dual-inhibitors of both associated functions of HIV-1 RT2013DISTINTO, SIMONA  ; CORONA, ANGELA  ; BIANCO, GIULIA  ; TRAMONTANO, ENZO  ; MACCIONI, ELIAS  4 Contributo in Atti di Convegno (Proceeding)::4.3 Poster-
A novel series of 3,4-disubstituted dihydropyrazoles: Synthesis and evaluation for MAO enzyme inhibition2013CARDIA, MARIA CRISTINA  ; SANNA, MARIA LUISA  ; MELEDDU, RITA  ; DISTINTO, SIMONA  ; MACCIONI, ELIAS  1 Contributo su Rivista::1.1 Articolo in rivista
Design, Synthesis and Biological Evaluation of New 1,3-Diarylpropenones as Single Site Dual Inhibitors of HIV-1 RT2013ESPOSITO, FRANCESCA  ; CANNAS, VALERIA  ; DISTINTO, SIMONA  ; CORONA, ANGELA  ; MACCIONI, ELIAS  ; TRAMONTANO, ENZO  4 Contributo in Atti di Convegno (Proceeding)::4.2 Abstract in Atti di convegno-
   
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