|Titolo:||Reversibility of fibrosis in Wilson disease|
|Data di pubblicazione:||2006|
|Abstract:||In contrast with the traditional view that liver ﬁbrosis should be considered an irreversible process, recent evidence indicates that even advanced hepatic ﬁbrosis could be regarded as a dynamic and reversible process, overturning the longstanding dogma that liver ﬁbrosis could never regress. This study was undertaken to evaluate ﬁbrosis evolution in patients affected by Wilson’s disease, in order to answer two main questions: 1) can liver ﬁbrosis reduce after anticopper treatment? and, 2) Is there any correlation between regression of ﬁbrosis and a speciﬁ ctherapy? Our study shows that liver ﬁbrosis, even in its advanced stage, should be regarded as a partially reversible process. This underscores the dynamic nature of liver ﬁbrosis in Wilson`s disease and offers hope for blocking progression of chronic liver disease even in the more advanced stages.|
|Tipologia:||1.1 Articolo in rivista|
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