Programma del Convegno
IV Meeting “Nuove Prospettive in Chimica Farmaceutica”
Giovedì 06/05/2010
8:30
Registrazione Partecipanti
9:00
Apertura dei Lavori Saluto delle Autorità
I Sessione: Metodi Computazionali in Chimica Farmaceutica
9:30
Prof. Vincenzo Barone: “Il ruolo della teoria nelle scienze molecolari”
10:05
Dott. Matteo Floris: “MMsINC: an alternative chemoproteomics amphitheater”
10:20
Dott.ssa Lucia Parrotta: “Molecular modeling of DNA G-quadruplex binders”
10:35
Dott.ssa Marta Del Cadia: “Computational analysis of ligand recognition sites of homo-and heteropentameric 5-HT3 receptors”
10:50
Coffee break/ Poster exhibition
II Sessione: Farmaci attivi sul SNC
11:05
Prof. Gaetano Di Chiara: “Principi farmacologici per lo sviluppo di antipsicotici atipici”
11:40
Dott.ssa Angela De Simone: “A multi-approach study for bace-1 inhibitors characterization”
11:55
Dott.ssa Francesca Rossi: “Synthesis, biological activity and molecular modeling studies of chalcones and flavones as potential monomine oxidase inhibitors ”
12:10
Dott. Gian Cesare Tron: “Discovery of a nanomolar inhibitor of NMPRTase by click chemistry”
12:25
Dott.ssa Isabella Pugliesi: “Novel 3-aryl-(1,2,4)triazino(4,3-a)benzimidazol-4(10H)-ones(ATBIs) as selective A2A adenosine receptor antagonists with neuroprotective effect”
12:40
Dott. Claudio Battilocchio: “1,5-diaryl-pyrroles as new generation of anti-inflammatory and analgesic agents: design, synthesis, in vitro and in vivo evaluation”
12:55
Dott.ssa Marina Sala: “Structure-activity relationship of CaMKIINtide peptide analogs
13:10
Dott.ssa Barbara Parrino: “Annelated azaindoles with antitumor activity”
13:30
Colazione di lavoro
III Sessione: Nuovi approcci terapeutici all’infezione da HIV-1
15:00
Prof. Enzo Tramontano: “New targets in the early phase of HIV-1 replication”
15:35
Dott. Valerio Gatti: “Indolylarylsulfones bearing natural and unnatural amino acids as inhibitors of HIV-1 reverse transcriptase and coxsackie B4 virus”
15:50
Dott. Giosuè Costa: “Computational analysis of HIV-1 reverse transcriptase complex”
16:05
Dott.ssa Irene Briguglio: “(1,2,3)-triazolo-(4,5H)-quinolones. A new class of potent antitubercular agents against multidrug resistant Mycobacterium tuberculosis strains”
16:20
Coffee Break/ Poster exhibition
IV Sessione: Nuovi Targets in Chimica Farmaceutica
Nuovi Farmaci Antitumorali
16:35
Prof. Claudia Martini: “Il mitocondrio nel controllo vita/morte della cellula”
17:10
Prof. Manlio Palumbo: “Nuovi farmaci antitumorali: luci e ombre”
17:45
Dott.ssa Maria Tardugno: “Biochemical, Structural, and Biological Evaluation of Tranylcypromine Derivatives as Inhibitors of Histone Demethylases LSD1 and LSD2”
18:00
Dott.ssa Stefania Sartini: “One-drug multi target activity. Pyrazolopyrimidine derivatives as antioxidant aldose reductase inhibitors”
18:15
Dott. Giovanni Marzaro: “Psoralenquinone proteasome inhibitors: design, synthesis and biological evaluation”
18:30
Dott. Andrea De Cupertinis: “New non steroidal agonists of estrogen receptor β”
18:45
Dott.ssa Sara Bendinelli: “Inhibition of mettalloproteinases derived from tumours: new insights in the treatment of human glioblastoma”
19:00
Dott. Antimo Gioiello: “New Potent and Selective FXR Agonists: Design, Synthesis and Modeling of Norcholanylamine Derivatives”
19:15
Dott.ssa Tracey Pirali: “Exploting the reactivity of α-isocyanoacetamides in diversity-oriented synthesis: an easy access to α-ketoamides and polysubstituted furans”
19:30
Dott. Marco Radi: “Playing around with the decoration of the pyrimidine scaffold: from Non-Nucleoside to Nucleotide-Competing RT Inhibitors”
20:30
Cena Sarda
Venerdì 07/05/2010
09:00
Prof. Giuseppe Ronsisvalle: “La qualità nella formazione dottorale e le reti europee”
V Sessione: Metodologie innovative nel Drug Discovery
09:20
Dott.ssa Luciana Marinelli:
09:55
Dott.ssa Maria Rosa Buemi: “Identification of indole derivatives as potent NR2B/NMDA receptor ligands”
10:10
Dott. Marco Tutone: “Inside c-kit tyrosine kinase: molecular modeling and QSAR in the search of new inhibitors”
10:25
Dott. Giovanni Bottegoni: “Multiple receptor conformations enhance early recognition in virtual ligand screening”
10:40
Coffee Break/ Poster exhibition
VI Sessione: Tecnologie analitiche innovative nel Drug Discovery
10:55
Prof.ssa Gabriella Massolini: “
11:30
Dott. Roccaldo Sardella: “Descriptive structure-separation relationship studies in the enantioseparation of amino acids”
11:45
Dott. Marco Pistolozzi: “HPALC and circular dichroism investigation of the tocainide analogues to human serum albumin”
12:00
Dott.ssa Sara Del Carlo: “Fluorimetric HPLC analysis of Valdecoxib and Parecoxib: preliminary data”
12:15
Dott.ssa Alessia Bertamino: “Synthesis of Novel Polycyclic Systems by Acid-Catalysed Condensation from a-Amino Aldehydes and L-aminoacids”
12:30
Dott.ssa Valentina Scanzani: “Sviluppo e validazione di un metodo in UHPLC di un prodotto farmaceutico”
12:45
Chiusura dei lavori
13:15
Colazione di lavoro