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Titolo: Cycloheximide prevents apomorphine-induced yawnin, penile erection and genital grooming in rats
Autori: 
Data di pubblicazione: 1983
Rivista: 
EUROPEAN JOURNAL OF PHARMACOLOGY  
Abstract: Apomorphine (50 micrograms/kg) induced repeated episodes of yawning, penile erection and genital grooming in rats. A dose of cycloheximide, which inhibited brain protein synthesis by 50% totally prevented apomorphine-induced yawning and reduced by approximately 50% the occurrence of episodes of penile erection and genital grooming. However, this treatment failed to modify the stereotyped behaviour induced by 200 micrograms/kg of apomorphine. These results suggest that protein synthesis is required for the behavioural effects of small doses of apomorphine.
Handle: http://hdl.handle.net/11584/1002
Tipologia:1.1 Articolo in rivista

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