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Mostra risultati da 21 a 40 di 51
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TitoloData di pubblicazioneAutore(i)RivistaEditore
Site directed mutagenesis studies on HIV-1 reverse transcriptase (RT) shed light on the mechanism of action of a new Ribonuclease H/ DNA polymerase RT dual inhibitor2013Corona, Angela; Meleddu, Rita; Esposito, Francesca; Distinto, Simona; Bianco, Giulia; Maccioni, E...lias; Le Grice, S.; Tramontano, EnzoRETROVIROLOGYBioMed Central Ltd
2-(2-cycloalkylidene hydrazin-1-yl)-4-aryl-1,3-thiazoles: a promising class of antifungal agents2013Arridu A.; Meleddu R.; Bianco G.; Distinto S.; De Logu A.; Matyus P.; Maccioni E
A novel series of 3,4-disubstituted dihydropyrazoles: Synthesis and evaluation for MAO enzyme inhibition2013Cardia, MARIA CRISTINA; Sanna, MARIA LUISA; Meleddu, Rita; Distinto, Simona; Yañez, M.; Viña, D.;... Lamela, M.; Maccioni, EliasJOURNAL OF HETEROCYCLIC CHEMISTRY
Molecular Aspects of the RT/drug Interactions. Perspective of Dual Inhibitors2013Distinto S; Maccioni E; Meleddu R; Corona A; Alcaro S; Tramontano ECURRENT PHARMACEUTICAL DESIGN
Synthesis and biological assessment of novel 2-thiazolylhydrazones and computational analysis of their recognition by monoamine oxidase B2012Distinto, Simona; Yáñez, M; Alcaro, S; Cardia, MARIA CRISTINA; Gaspari, M; Sanna, MARIA LUISA; Me...leddu, Rita; Ortuso, F; Kirchmair, J; Markt, P; Bolasco, A; Wolber, G; Secci, D; Maccioni, EliasEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Mutagenic study on HIV-1 reverse transcriptase to explore the mechanism of action of HIV-1 reverse transcriptase dual inhibitors2012Corona A.; Meleddu R.; Esposito F.; Sanna M. L.; Distinto S.; Maccioni E; Tramontano E.
3-Acetyl-2,5-diaryl-2,3-dihydro-1,3,4-oxadiazoles: A new scaffold for the selective inhibition of monoamine oxidase B2011Maccioni, Elias; Alcaro, S.; Cirilli, R.; Vigo, S.; Cardia, MARIA CRISTINA; Sanna, MARIA LUISA; M...eleddu, Rita; Yanez, M.; Costa, G.; Casu, Laura; Matyus, P.; Distinto, SimonaJOURNAL OF MEDICINAL CHEMISTRY
Design and synthesis of new isatin derivatives as HIV-1 reverse transcriptase associated ribonuclease H inhibitors2011F. Esposito; R. Meleddu; M.L. Sanna; S. Distinto; A. Corona; V. Cannas; E. Tramontano; M.C. CardiaANTIVIRAL RESEARCH
New promising scaffolds for the inhibition of monoamine oxidase B2011Sanna M. L.; Meleddu R.; Cardia M.C.; Distinto S.; Alcaro S.; Maccioni E
Semicarbazide-sensitive amine oxidase/vascular adhesion protein-1: a patent survey2011Dunkel, P; Balogh, B; Meleddu, Rita; Maccioni, Elias; Gyires, K; Mátyus, P.EXPERT OPINION ON THERAPEUTIC PATENTS
Design, synthesis and biolgical activity evaluation of new HIV-1 reverse transcriptase dual inhibitors2011Meleddu R; Corona A; Sanna M L; Esposito F; Cardia M C; Tramontano E; Maccioni E
Isatin derivatives as new scaffolds for HIV-1 reverse transcriptase associated RNase H and RDDP dual inhibitors2011Corona A.; Meleddu R.; Esposito F.; Sanna M. L.; Distinto S; Maccioni E.; Tramontano E.
3-[2-(4-aryl-1,3-thiazol-2-yl)hydrazin-1-ylidene]-1H-indol-2-ones as new potential dual inhibitors of polimerase and ribonuclease HIV-1 RT associated function2011Meleddu R.; Corona A.; Distinto S; Esposito F.; Sanna M. L.; Cardia C.; Tramontano E.; Maccioni E.
Design and synthesis of new Isatin derivatives as HIV-1 Reverse Transcriptase associated Ribonuclease H inhibitors twenty-fourth2011Esposito F; Meleddu R; Sanna M L; Distinto S; Corona A; Cannas V; Tramontano E; Cardia M C
Chalcones as novel dual inhibitors of HIV-1 reverse transcriptase2011Meleddu R.; Corona A.; Esposito F.; Tramontano E.; Distinto S; Sanna M. L.; Cardia C.; Alcaro S.;... Maccioni E.
Exploring new scaffolds for the inibition of the Ribonuclease H function of RT HIV-12011Meleddu R; Corona A; Distinto S; Esposito F; Sanna M L; Cardia M C; Tramontano E; Maccioni E
Design of new inhibitors of the HIV-1 Reverse Transcriptase associated Ribonuclease H function: a synthetic approach2010Meleddu R.; Sanna M.L.; Distinto S; Esposito F.; Corona A.; Ortuso F.; Alcaro S.; Maccioni E.; Ca...rdia M.C.; Tramontano E.
Synthesis of new 3-aryl-4,5-dihydropyrazole-1-carbothioamide derivatives. An investigation on their ability to inhibit monoamine oxidase2010MACCIONI E; S. ALCARO; F. ORALLO; M.C. CARDIA; S. DISTINTO; G. COSTA; M. YANEZ; M.L. SANNA; S. VI...GO; R. MELEDDU; D. SECCIEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
SYNTHESIS, MOLECULAR MODELLING, INHIBITORY ACTIVITY, AND SELECTIVITY TOWARDS MONOAMINE OXIDASE OF NEW HETEROCYCLIC SCAFFOLDS2010Sanna M.L; Maccioni E; Alcaro S; Cirilli R; Ferretti R; Yanez M; Cardia M. C; Distinto S; Meleddu... R; Vigo S; Ortuso F.
Identification of new scaffolds for the inhibition of HIV-1 Reverse Transcriptase associated Ribonuclease H function by means of shape based similarity screening2010Distinto S; Esposito F.; Maccioni E.; Cardia M.C.; Markt P.; Tramontano E.; Sanna M.L.; Meleddu R.
   
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