Prodotti della ricerca
UNICA IRIS Institutional Research Information System
IRIS è il sistema di gestione integrata dei dati della ricerca (persone, progetti, pubblicazioni, attività) adottato dall'Università degli Studi di Cagliari dal mese di luglio 2015.
| Titolo | Data di pubblicazione | Autore(i) | Rivista | Editore |
|---|---|---|---|---|
| Discovery of dihydroxyindole-2-carboxylic acid derivatives as dual allosteric HIV-1 Integrase and Reverse Transcriptase associated Ribonuclease H inhibitors | 2020 | Esposito, Francesca; Sechi, Mario; Pala, Nicolino; Sanna, Adele; Koneru, Pratibha Chowdary; Kvara...tskhelia, Mamuka; Naesens, Lieve; Corona, Angela; Grandi, Nicole; di Santo, Roberto; D'Amore, Vincenzo Maria; Di Leva, Francesco Saverio; Novellino, Ettore; Cosconati, Sandro; Tramontano, Enzo | ANTIVIRAL RESEARCH | |
| Targeting HIV-1 RNase H: N'-(2-Hydroxy-benzylidene)-3,4,5-Trihydroxybenzoylhydrazone as Selective Inhibitor Active against NNRTIs-Resistant Variants | 2020 | Corona, Angela; Ballana, Ester; Distinto, Simona; Rogolino, Dominga; Del Vecchio, Claudia; Carcel...li, Mauro; Badia, Roger; Riveira-Muñoz, Eva; Esposito, Francesca; Parolin, Cristina; Esté, José A; Grandi, Nicole; Tramontano, Enzo | VIRUSES | |
| 2-(Arylamino)-6-(trifluoromethyl)nicotinic Acid Derivatives: New HIV-1 RT Dual Inhibitors Active on Viral Replication | 2020 | Corona, Angela; Onnis, Valentina; Del Vecchio, Claudia; Esposito, Francesca; Cheng, Yung-Chi; Tra...montano, Enzo | MOLECULES | |
| Scaffold hopping and optimisation of 3’,4’-dihydroxyphenyl- containing thienopyrimidinones: synthesis of quinazolinone derivatives as novel allosteric inhibitors of HIV-1 reverse transcriptase-associated ribonuclease H | 2020 | Tocco, Graziella; Esposito, Francesca; Caboni, Pierluigi; Laus, Antonio; Beutler, John A.; Wilson..., Jennifer A.; Corona, Angela; Le Grice, Stuart F. J.; Tramontano, Enzo | JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY | |
| Pyrrolyl Pyrazoles as Non-Diketo Acid Inhibitors of the HIV-1 Ribonuclease H Function of Reverse Transcriptase | 2020 | Messore, Antonella; Corona, Angela; Madia, Valentina Noemi; Saccoliti, Francesco; Tudino, Valeria...; De Leo, Alessandro; Scipione, Luigi; De Vita, Daniela; Amendola, Giorgio; Di Maro, Salvatore; Novellino, Ettore; Cosconati, Sandro; Métifiot, Mathieu; Andreola, Marie-Line; Valenti, Piera; Esposito, Francesca; Grandi, Nicole; Tramontano, Enzo; Costi, Roberta; Di Santo, Roberto | ACS MEDICINAL CHEMISTRY LETTERS | |
| Development of a Raltegravir-based Photoaffinity-Labeled Probe for Human Immunodeficiency Virus-1 Integrase Capture | 2020 | Pala, Nicolino; Esposito, Francesca; Tramontano, Enzo; Kumar Singh, Pankaj; Sanna, Vanna; Carcell...i, Mauro; Haigh, Lisa D.; Satta, Sandro; Mario Sechi, And | ACS MEDICINAL CHEMISTRY LETTERS | |
| Dual HIV-1 reverse transcriptase and integrase inhibitors from Limonium morisianum Arrigoni, an endemic species of Sardinia (Italy) | 2019 | SANNA, CINZIA; Rigano, Daniela; CORONA, ANGELA; PIANO, DARIO; Formisano, Carmen; FARCI, DOMENICA;... Franzini, Genni; BALLERO, MAURO; Chianese, Giuseppina; TRAMONTANO, ENZO; Taglialatela-Scafati, Orazio; ESPOSITO, FRANCESCA | NATURAL PRODUCT RESEARCH | |
| Chromenone derivatives as a versatile scaffold with dual mode of inhibition of HIV-1 reverse transcriptase-associated Ribonuclease H function and integrase activity | 2019 | Esposito, F.; Ambrosio, F. A.; Maleddu, R.; Costa, G.; Rocca, R.; Maccioni, E.; Catalano, R.; Rom...eo, I.; Eleftheriou, P.; Karia, D. C.; Tsirides, P.; Godvani, N.; Pandya, H.; Corona, A.; Alcaro, S.; Artese, A.; Geronikaki, A.; Tramontano, E. | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | |
| Identification of Myricetin as Ebolavirus VP35-dsRNA interaction inhibitor through a novel fluorescence-based assay | 2018 | Luca Daino, Gian; Frau, Aldo; Sanna, Cinzia; Rigano, Daniela; Distinto, Simona; Madau, Veronica; ...Esposito, Francesca; Fanunza, Elisa; Bianco, Giulia; Taglialatela-Scafati, Orazio; Zinzula, Luca; Maccioni, Elias; Corona, Angela; Tramontano, Enzo | BIOCHEMISTRY | |
| Onopordum illyricum L., a Mediterranean plant, as a source of anti HIV-1 compounds | 2018 | Sanna, C.; Rigano, D.; Cortis, P.; Corona, A.; Ballero, M.; Parolin, C.; Del Vecchio, C.; Chianes...e, G.; Saccon, E.; Formisano, C.; Tramontano, E.; Esposito, F. | PLANT BIOSYSTEMS | |
| On the S-layer of Thermus thermophilus and the assembling of its main protein SIpA | 2018 | Farci, Domenica; Farci, Stefano Francesco; Esposito, Francesca; Tramontano, Enzo; Kirkpatrick, Jo...anna; Piano, Dario | BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES | |
| Structure-guided approach identifies a novel class of HIV-1 Ribonuclease H inhibitors: Binding mode insights through magnesium complexation and site-directed mutagenesis studies | 2018 | Poongavanam, Vasanthanathan; Corona, Angela; Svendsen, Casper; Scipione, Luigi; Grandi, Nicole; P...andolfi, Fabiana; Di Santo, Roberto; Costi, Roberta; Esposito, Francesca; Tramontano, Enzo; Kongsted, Jacob | MEDCHEMCOMM | |
| Improvement of the activity of the anti-HIV-1 integrase aptamer T30175 by introducing a modified thymidine into the loops | 2018 | Virgilio, Antonella; Amato, Teresa; Petraccone, Luigi; Esposito, Francesca; Grandi, Nicole; Tramo...ntano, Enzo; Romero, Raquel; Haider, Shozeb; Gomez-Monterrey, Isabel; Novellino, Ettore; Mayol, Luciano; Esposito, Veronica; Galeone, Aldo | SCIENTIFIC REPORTS | |
| Prenylated phloroglucinols from Hypericum scruglii, an endemic species of Sardinia (Italy), as new dual HIV-1 inhibitors effective on HIV-1 replication | 2018 | Sanna, Cinzia; Scognamiglio, Monica; Fiorentino, Antonio; Corona, Angela; Graziani, Vittoria; Car...edda, Alessia; Cortis, Pierluigi; Montisci, Mariofilippo; Rita Ceresola, Elisa; Canducci, Filippo; Poli, Ferruccio; Tramontano, Enzo; Esposito, Francesca | PLOS ONE | |
| New insights into the operative network of FaEO, an enone oxidoreductase from Fragaria x ananassa Duch | 2017 | Collu, Gabriella; Farci, Domenica; Esposito, Francesca; Pintus, Francesca; Kirkpatrick, Joanna; P...iano, Dario | PLANT MOLECULAR BIOLOGY | |
| Chelation motifs affecting metal-dependent viral enzymes: N′-acylhydrazone ligands as dual target inhibitors of HIV-1 Integrase and Reverse Transcriptase Ribonuclease H domain | 2017 | Carcelli, Mauro; Rogolino, Dominga; Gatti, Anna; Pala, Nicolino; Corona, Angela; Caredda, Alessia...; Tramontano, Enzo; Pannecouque, Christophe; Naesens, Lieve; Esposito, Francesca | FRONTIERS IN MICROBIOLOGY | |
| Identification of a novel HERV-K(HML10): comprehensive characterization and comparative analysis in non-human primates provide insights about HML10 proviruses structure and diffusion | 2017 | Grandi, Nicole; Cadeddu, Marta; Pisano, Maria Paola; Esposito, Francesca; Blomberg, Jonas; Tramon...tano, Enzo | MOBILE DNA | |
| Natural Product Kuwanon-L Inhibits HIV-1 Replication through Multiple Target Binding | 2017 | Martini, Riccardo; Esposito, Francesca; Corona, Angela; Ferrarese, Roberto; Ceresola, Elisa Rita;... Visconti, Laura; Tintori, Cristina; Barbieri, Alessandro; Calcaterra, Andrea; Iovine, Valentina; Canducci, Filippo; Tramontano, Enzo; Botta, Maurizio | CHEMBIOCHEM | |
| S-layer proteins as a source of carotenoids: Isolation of the carotenoid cofactor deinoxanthin from its S-layer protein DR_2577 | 2017 | Farci, Domenica; Esposito, Francesca; El Alaoui, Sabah; Piano, Dario | FOOD RESEARCH INTERNATIONAL | |
| Multi-target activity of Hemidesmus indicus decoction against innovative HIV-1 drug targets and characterization of Lupeol mode of action | 2017 | Esposito, Francesca; Mandrone, Manuela; Del Vecchio, Claudia; Carli, Ilaria; Distinto, Simona; Co...rona, Angela; Lianza, Mariacaterina; Piano, Dario; Tacchini, Massimo; Maccioni, Elias; Cottiglia, Filippo; Saccon, Elisa; Poli, Ferruccio; Parolin, Cristina; Tramontano, Enzo | PATHOGENS AND DISEASE |
