Research Topics

 

Theme 1) NEUROBIOLOGY

  • Genetics of Alzheimer’s disease
  • Genetics of primary headaches: migraine and cluster headache.
  • Genetics of Schizophrenia and Bipolar disease
  • Neurobiological mechanisms underlying alcoholism
  • Neurobiology of nicotine addiction: involvement of the endocannabinoid system and its modulation by nuclear receptors
  • Neurobiology of anxiety disorders.
  • Role of the endocannabinoid system in eating disorders , mood disorders and in the processes of drug dependence

Theme 2) NEUROPSYCHOPHARMACOLOGY

  • Epigenetic effects of lithium
  • Pharmacogenetics of mood-stabilizing medications in the treatment of Bipolar Disorder
  • Pharmacogenomics of suicide : study of the of polyamine system
  • Cannabinoid – nicotine interaction in the mechanisms of dependence and relapse to substance use
  • Mechanisms of antipsychotic -like finasteride
  • Role of the basic mechanisms of neurodegeneration and cognitive impairments that accompany the abuse of methamphetamine.
  • Study of the long-term consequences of drug intake during adolescence
  • The chemical synthesis and pharmacological characterization of new allosteric modulators of the GABAB receptor .
  • Assessment of the risk of lithium treatment in pregnancy

 

Theme 3 ) NEUROPHYSIOLOGY

  • Adaptation of limbic neurons to chronic neuropathic pain
  • Functional and molecular characterization of the endocannabinoid system in the limbic regions.
  • Co -release of dopamine and noradrenaline from noradrenergic neurons in the cerebral cortex
  • Study of the neural mechanisms underlying the neuropsychiatric diseases
  • Study of interactions between nuclear receptors PPAR -alpha and nicotinic cholinergic receptors.

 

Theme 4 ) BEHAVIORAL NEUROSCIENCE

  • Central control of erectile function and sexual behavior
  • Interaction neurotransmitters – neuropeptides in central control of erectile function
  • New neuroendocrine peptides : involvement in the sexual response in food intake and
  • Schizophrenia and the endocannabinoid system : behavioral studies
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