|Abstract: ||This study proposes to characterize the gait patterns of individuals with Multiple Sclerosis (MS) affected
by spasticity using quantitative gait analysis.
Method: Cross-sectional study on 38 individuals with MS, 19 affected by lower limb spasticity and 19 not affected,
the latter forming the control group. Both groups were evaluated while walking using three-dimensional gait
analysis. Spatio-temporal parameters of gait, kinematic data expressed by means of Gait Profile Score (GPS)
and Range of Motion (ROM), as well as muscular activation, were evaluated.
Results: The results show that spasticity originates a peculiar gait pattern characterized by reduced speed,
cadence, stride length, swing phase and increased double support time, but they also reveal specific alterations
in kinematics and muscular activation. In particular, significantly higher values of GPS, reduced hip and knee
flexion-extension ROM and abnormal activation of the rectus femoris were observed in individuals with spasticity.
Conclusions: In people with MS presenting spastic gait, the availability of quantitative data appears crucial in verifying
the effectiveness of pharmacologic and rehabilitative treatments, also considering that spasticity scales may
not be satisfactory in relating the assessed spasticity with both perception of the patients and the actual body