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Titolo: Ultrastructural localization of glycodelin oligosaccharides Le-x and Le-y in human seminal vesicles by immunogold staining
Autori: 
Data di pubblicazione: 2007
Rivista: 
JOURNAL OF ANATOMY  
Citazione: Ultrastructural localization of glycodelin oligosaccharides Le-x and Le-y in human seminal vesicles by immunogold staining / PILUDU M; COSSU M; DE LISA A; PIRAS M; LANTINI MS. - 210:3(2007), pp. 352-356.
Abstract: Histo-blood group antigens Le-x and Le-y are oligosaccharidic terminals that characterize many glycoproteins in the human tissues. In seminal plasma, they are expressed as part of the so-called glycodelin S, which is suggested to regulate sperm capacitation/decapacitation. It has recently been demonstrated that the core protein of glycodelin S is secreted by seminal vesicles. Here we show that epithelial cells of human seminal vesicles also release the Le-x and Le-y antigens. The presence of these substances in secretory material was revealed by means of an immunogold staining method in normal surgical samples. The results suggest that glycodelin S is secreted by seminal vesicles in its finished glycosylated form. Moreover, antigen reactivity was also revealed associated with plasma membranes.
Handle: http://hdl.handle.net/11584/104817
Tipologia:1.1 Articolo in rivista

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