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TitoloData di pubblicazioneAutore(i)RivistaEditore
Overexpression of the cytokine BAFF and autoimmunity risk2017Steri, M; Orru', Valeria; Idda, Ml; Pitzalis, M.; Pala, Mauro; Zara, I; Sidore, C; Faà, V; Floris..., M; Deiana, M; Asunis, I; Porcu, E; Mulas, A; Piras, Mg; Lobina, M; Lai, S; Marongiu, Mara; Serra, V; Marongiu, M; Sole, G; Busonero, Fabio; Maschio, A; Cusano, Roberto; Cuccuru, G; Deidda, Francesca; Poddie, F; Farina, Gabriele; Dei, M; Virdis, F; Olla, S; Satta, Ma; Pani, M; Delitala, A; Cocco, Eleonora; Frau, Jessica; Coghe, Giancarlo; Lorefice, Lorena; Fenu, Giuseppe; Ferrigno, P; Ban, M; Barizzone, N; Leone, M; Guerini, Fr; Piga, Matteo; Firinu, Davide; Kockum, I; Lima, B; Olsson, T; Alfredsson, L; Suarez, A; Carreira, Pe; Castillo Palma, Mj; Marcus, Jh; Congia, Mauro; Angius, Andrea; Melis, M; Gonzalez, A; Alarcón Riquelme, Me; Da Silva, Bm; Marchini, M; Danieli, Mg; DEL GIACCO, Stefano; Mathieu, Alessandro; Pani, A; Montgomery, Sb; Rosati, G; Hillert, ; J., Sawcer; S, ; D'Alfonso, S; Todd, Ja; Novembre, J; Abecasis, Gr; Whalen, MICHAEL BERNARD; Marrosu, MARIA GIOVANNA; Meloni, Alessandra; Sanna, S; Gorospe, M; Schlessinger, D; Fiorillo, Edoardo; Zoledziewska, M; Cucca, F.NEW ENGLAND JOURNAL OF MEDICINE
LYP-W620 Does Not Impair Thymic Negative Selection of Autoreactive T Cells2014Wu DJ; Zhou W; Enouz S; ORRU' V; Stanford SM; Maine CJ; Rapini N; Sawatzke K; Engel I; Fiorillo E...; Sherman LA; Kronenberg M; Zehn D; Peterson E; Bottini N.PLOS ONE
Effects of aging and sex difference on immune-related phenotypes2013Sole G; Orrù V; Fiorillo E; Steri M; Dei M; Lai S; Virdis F; Schlessinger D; Cucca F; Sanna SEUROPEAN JOURNAL OF HUMAN GENETICS
System and pathway analysis of variants associated with immune cell levels2013Mentzen WI; Floris M.; Orru' V; Ster M; Sole G; Urru SAM; Olla S; Virdis F; Dei M; Lai S; Fiorill...o E; Sanna S; Cucca FEUROPEAN JOURNAL OF HUMAN GENETICS
Genetic variants regulating immune cell levels in health and disease2013Orru', Valeria; Steri, M; Sole, G; Sidore, C; Virdis, F; Dei, M; Lai, S; Zoledziewska, M; Busoner...o, F; Mulas, A; Floris, M; Mentzen, Wi; Urru, S; Olla, S; Marongiu, M; Piras, Mg; Lobina, M; Maschio, A; Pitzalis, M; Urru, Mf; Marcelli, M; Cusano, R; Deidda, F; Serra, V; Oppo, M; Pilu, R; Reinier, F; Berutti, R; Pireddu, L; Zara, I; Porcu, E; Kwong, A; Brennan, C; Tarrier, B; Lyons, R; Kang, Hm; Uzzau, S; Atzeni, R; Valentini, M; Firinu, Davide; Leoni, L; Rotta, G; Naitza, S; Angius, A; Congia, M; Whalen, Mb; Jones, Cm; Schlessinger, D; Abecasis, Gr; Fiorillo, Edoardo; Sanna, S; Cucca, F.CELL
Genetic factors associated with levels of immune cell types2012M. Steri; V. Orrù; Fiorillo E; G. Sole; C. Sidore; F. Virdis; M. Dei; S. Lai; A. Mulas; M.G. Pira...s; M. Lobina; M. Marongiu; M. Zoledziewska; M. Congia; F. Busonero; A. Maschio; M.F. Urru; M. Marcelli; R. Atzeni; D. Firinu; M. Valentini; W. Mentzen; S. Naitza; M.B. Whalen; A. Angius; C.M. Jones; D. Schlessinger; G. Abecasis; S. Sanna; F. Cucca
Systematic assessment of the immune system by genetic mapping of its quantitative dimensions2012Sanna S; Steri M; Sole G; Sidore C; Urru MF; Busonero F; Reinier F; Dei M; Lai S; Virdis F; Mulas... A; Marcelli M; Atzeni R; Angius A; Jones CM; Schlessinger D; Abecasis GR; Orru' V; Fiorillo E; Cucca FEUROPEAN JOURNAL OF HUMAN GENETICS
A comprehensive phenotypic and genetic analysis of centenarians from 13 Villages located in the Sardinian region of Barbagia-Mandrolisai2012Urru SAM; Ferreli L; Zedda G; N. Curreli; Piras M; Lobina M; Marongiu M; Floris M; Sanna S; Orru'... V; Fiorillo E; Galanello R; Atzeni A; Pani A; Cucca FEUROPEAN JOURNAL OF HUMAN GENETICS
Heritability and genetic mapping of hundreds of immune-related quantitative traits measured in a large Sardinian cohort2011Sanna S; Sole G; Steri M; Dei M; Lai S; Virdis F; Schlessinger D; Congia M; Naitza S; Orru' V; Fi...orillo E; Cucca F
Number of autoantibodies and HLA genotype, more than high titers of glutamic acid Decarboxylase autoantibodies (GADA65Ab), predict insulin-dependence in Latent Autoimmune Diabetes of Adults (LADA)2010MAIOLI M; PES GM; DELITALA G; PUDDU L; FALORNI A; TOLU F; LAMPIS R; ORRÙ V; SECCHI G; CICALÒ AM; ...FLORIS R; MADAU GF; PILOSU RM; WHALEN M; CUCCA FEUROPEAN JOURNAL OF ENDOCRINOLOGY
Autoimmune-associated PTPN22 R620W variation reduces phosphorylation of lymphoid phosphatase on an inhibitory tyrosine residue2010FIORILLO E; ORRÙ V; STANFORD SM; LIU Y; SALEK M; RAPINI N; SCHENONE AD; SACCUCCI P; DELOGU LG; AN...GELINI F; MANCA BITTI ML; SCHMEDT C; CHAN AC; ACUTO O; BOTTINI N
A loss-of-function variant of PTPN22 is associated with reduced risk of systemic lupus erythematosus2009ORRÚ V; TSAI SJ; RUEDA B; FIORILLO E; STANFORD SM; DASGUPTA J; HARTIALA J; ZHAO L; ORTEGO-CENTENO... N; D'ALFONSO S; ITALIAN COLLABORATIVE GROUP; ARNETT FC; WU H; GONZALEZ-GAY MA; TSAO BP; PONS-ESTEL B; ALARCON-RIQUELME ME; HE Y; ZHANG ZY; ALLAYEE H; CHEN XS; MARTIN J; BOTTINI NHUMAN MOLECULAR GENETICS
Autoimmune-associated LYP-W620 variant reduces T cell activation by altering a recirpocal feedback mechanism2009Fiorillo E; Orrù V.; Liu Y.; Stanford S.; Salek M.; Rapini N.; Delogu L.; Saccucci P.; Angelini F....; Manca Bitti M.; Rosatelli M. C.; Acuto O.; Bottini NEUROPEAN JOURNAL OF HUMAN GENETICS
Whole-gene expression system by RMCE-mediated integration of PAC clones2009Orru' V; Fiorillo E; Stanford S; Cucca F; Bottini NEUROPEAN JOURNAL OF HUMAN GENETICS
Crystal structure of the human lymphoid tyrosine phosphatase catalytic domain: insights into redox regulation2009TSAI SJ; SEN U; ZHAO L; GREENLEAF WB; DASGUPTA J; FIORILLO E; ORRÚ V; BOTTINI N; CHEN XSBIOCHEMISTRY
Regulation of lymphoid tyrosine phosphatase activity: inhibition of the catalytic domain by the proximal interdomain2009LIU Y; STANFORD SM; JOG SP; FIORILLO E; ORRÚ V; COMAI L; BOTTINI NBIOCHEMISTRY
La variante proteica associata all’autoimmunità LYP-W620 riduce l’attivazione delle cellule T mediante l’alterazione della regolazione reciproca tra LYP ed Lck2008Fiorillo E; Orru' V; Liu Y; Standford S; Salek M; Rapini N; Delogu L; Saccucci P; Angelici F; Bit...ti ML; Rosatelli C; Acuto O; Bottini N
Further evidence of a primary, causal association of the PTPN22 620W variant with type 1 diabetes2008ZOLEDZIEWSKA M; PERRA C; ORRÙ V; MOI L; FRONGIA P; CONGIA M; BOTTINI N; AND CUCCA FDIABETES
Gold(I)-mediated inhibition of protein tyrosine phosphatases: a detailed in vitro and cellular study2008KRISHNAMURTHY D; KARVER MR; FIORILLO E; ORRÚ V; STANFORD SM; BOTTINI N; BARRIOS AMJOURNAL OF MEDICINAL CHEMISTRY
Functional Characterization of the Autoimmune-associated LYP-W620 Variant2007Zhao L; Liu Y; Fiorillo E; Stanford S; Orrù V; Bottini NCLINICAL IMMUNOLOGY
   
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