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IRIS è il sistema di gestione integrata dei dati della ricerca (persone, progetti, pubblicazioni, attività) adottato dall'Università degli Studi di Cagliari dal mese di luglio 2015.

Mostra risultati da 1 a 20 di 143
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TitoloData di pubblicazioneAutore(i)RivistaEditore
The challenge of intracellular antibiotic accumulation, a function of fluoroquinolone influx versus bacterial efflux2020Vergalli, J.; Atzori, A.; Pajovic, J.; Dumont, E.; Malloci, G.; Masi, M.; Vargiu, A. V.; Winterha...lter, M.; Refregiers, M.; Ruggerone, P.; Pages, J. -M.COMMUNICATIONS BIOLOGY
Molecular interactions of carbapenem antibiotics with the multidrug efflux transporter acrb of escherichia coli2020Atzori, A.; Malloci, G.; Cardamone, F.; Bosin, A.; Vargiu, A. V.; Ruggerone, P.INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Cryo-EM structure and molecular dynamics analysis of the fluoroquinolone resistant mutant of the acrb transporter from salmonella2020Johnson, R. M.; Fais, C.; Parmar, M.; Cheruvara, H.; Marshall, R. L.; Hesketh, S. J.; Feasey, M. ...C.; Ruggerone, P.; Vargiu, A. V.; Postis, V. L. G.; Muench, S. P.; Bavro, V. N.MICROORGANISMS
Chlorpromazine and amitriptyline are substrates and inhibitors of the acrb multidrug efflux pump2020Grimsey, E. M.; Fais, C.; Marshall, R. L.; Ricci, V.; Ciusa, M. L.; Stone, J. W.; Ivens, A.; Mall...oci, G.; Ruggerone, P.; Vargiu, A. V.; Piddock, L. J. V.MBIO
Binding and Transport of Carboxylated Drugs by the Multidrug Transporter AcrB2020Tam, HK; Malviya, VN; Foong, WE; Herrmann, A; Malloci, G; Ruggerone, P; Vargiu, AV; Pos, KMJOURNAL OF MOLECULAR BIOLOGY
Identification and characterization of carbapenem binding sites within the RND-transporter AcrB2019Atzori, Alessio; Malviya, Viveka N.; Malloci, Giuliano; Dreier, Jürg; Pos, Klaas M.; Vargiu, Atti...lio V.; Ruggerone, PaoloBIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
Relevance of Ebola virus VP35 homo-dimerization on the type I interferon cascade inhibition2019Di Palma, Francesco; Daino, Gian Luca; Ramaswamy, Venkata Krishnan; Corona, Angela; Frau, Aldo; F...anunza, Elisa; Vargiu, Attilio V; Tramontano, Enzo; Ruggerone, PaoloANTIVIRAL CHEMISTRY & CHEMOTHERAPY
Molecular Interactions of Cephalosporins with the Deep Binding Pocket of the RND Transporter AcrB2019Atzori, Alessio; Malloci, Giuliano; Dahyabhai Prajapati, Jigneshkumar; Basciu, Andrea; Bosin, And...rea; Kleinekathöfer, Ulrich; Dreier, Jürg; Vargiu, Attilio V.; Ruggerone, PaoloJOURNAL OF PHYSICAL CHEMISTRY. B, CONDENSED MATTER, MATERIALS, SURFACES, INTERFACES & BIOPHYSICAL
Molecular basis for the different interactions of congeneric substrates with the polyspecific transporter AcrB2019Malvacio, Ivana; Rosa, Buonfiglio; Noemi, D'Atanasio; Serra, Giovanni; Bosin, Andrea; Francesco P...aolo Di Giorgio, ; Ruggerone, Paolo; Rosella, Ombrato; Vargiu, ATTILIO VITTORIOBIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
Water-mediated interactions enable smooth substrate transport in a bacterial efflux pump2018Vargiu, Attilio Vittorio; Ramaswamy, Venkata Krishnan; Malvacio, Ivana; Malloci, Giuliano; Kleine...kathöfer, Ulrich; Ruggerone, PaoloBIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
Molecular Modeling of Multidrug Properties of Resistance Nodulation Division (RND) Transporters2018Cacciotto, Pierpaolo; Ramaswamy, Venkata K; Malloci, Giuliano; Ruggerone, Paolo; Vargiu, Attilio V.Humana Press
A New Critical Conformational Determinant of Multidrug Efflux by an MFS Transporter2018Zomot, Elia; Yardeni, Eliane Hadas; Vargiu, Attilio Vittorio; Tam, Heng-Keat; Malloci, Giuliano; ...Ramaswamy, Venkata Krishnan; Perach, Michal; Ruggerone, Paolo; Pos, Klaas Martinus; Bibi, EitanJOURNAL OF MOLECULAR BIOLOGY
Molecular Determinants of the Promiscuity of MexB and MexY Multidrug Transporters of Pseudomonas aeruginosa2018Ramaswamy, Venkata K.; Vargiu, Attilio V.; Malloci, Giuliano; Dreier, Jürg; Ruggerone, PaoloFRONTIERS IN MICROBIOLOGY
Insights into Ebola VP35 oligomerization from molecular simulations2018DI PALMA, Francesco; Ramaswamy, VENKATA KRISHNAN; Daino, Gianluca; Frau, Aldo; Corona, Angela; Zi...nzula, Luca; Tramontano, Enzo; Ruggerone, Paolo; Vargiu, ATTILIO VITTORIOABSTRACTS OF PAPERS - AMERICAN CHEMICAL SOCIETYAMER CHEMICAL SOC
Computer simulations of the activity of RND efflux pumps2018Vargiu, Attilio Vittorio; Ramaswamy, Venkata Krishnan; Malloci, Giuliano; Malvacio, Ivana; Atzori..., Alessio; Ruggerone, PaoloRESEARCH IN MICROBIOLOGY
Insights into the homo-oligomerization properties of N-terminal coiled-coil domain of Ebola virus VP35 protein2018Ramaswamy, VENKATA KRISHNAN; DI PALMA, Francesco; Vargiu, Attilio V.; Corona, Angela; Piano, Dari...o; Ruggerone, Paolo; Zinzula, Luca; Tramontano, EnzoVIRUS RESEARCH
Computational modelling of efflux pumps and their inhibitors2017Ramaswamy, Venkata Krishnan; Cacciotto, Pierpaolo; Malloci, Giuliano; Vargiu, Attilio V.; Ruggero...ne, PaoloESSAYS IN BIOCHEMISTRY
Molecular Rationale behind the Differential Substrate Specificity of Bacterial RND Multi-Drug Transporters2017Ramaswamy, Venkata Krishnan; Vargiu, Attilio V.; Malloci, Giuliano; Dreier, Jürg; Ruggerone, PaoloSCIENTIFIC REPORTS
Molecular basis for inhibition of AcrB multidrug efflux pump by novel and powerful pyranopyridine derivatives2016Sjuts, Hanno; Vargiu, Attilio V; Kwasny, Steven M.; Nguyen, Son T.; Kim, Hong-Suk; Ding, Xiaoyuan...; Ornik, Alina R.; Ruggerone, Paolo; Bowlin, Terry L.; Nikaido, Hiroshi; Pos, Klaas M.; Opperman, Timothy J.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Multidrug efflux pumps and their inhibitors characterized by computational modeling2016Ramaswamy, VENKATA KRISHNAN; Cacciotto, Pierpaolo; Malloci, Giuliano; Ruggerone, Paolo; Vargiu, A...TTILIO VITTORIOSpringer
   
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