|Titolo:||Mild Synthetic Approach to Novel Indole-1-Carbinols and Preliminary Evaluation of Their Cytotoxicity in Hepatocarcinoma Cells|
|Data di pubblicazione:||2012|
|Abstract:||A mild and versatile method for the synthesis of some novel indole-1-carbinols has been developed via one-pot reaction of indoles and paraformaldehyde in the presence of an excess of CaO, MgO, ZnO or TiO2. The solvent-free reaction provided all the indole derivatives in moderate to good yields and short reaction times. Moreover, the effect of some selected indole-1-carbinols on cell proliferation of the hepatoma cell line FaO was evaluated.|
|Tipologia:||1.1 Articolo in rivista|
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