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IRIS è il sistema di gestione integrata dei dati della ricerca (persone, progetti, pubblicazioni, attività) adottato dall'Università degli Studi di Cagliari dal mese di luglio 2015.

Mostra risultati da 21 a 40 di 97
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TitoloData di pubblicazioneAutore(i)RivistaEditore
Identification of Myricetin as Ebolavirus VP35-dsRNA interaction inhibitor through a novel fluorescence-based assay2018Luca Daino, Gian; Frau, Aldo; Sanna, Cinzia; Rigano, Daniela; Distinto, Simona; Madau, Veronica; ...Esposito, Francesca; Fanunza, Elisa; Bianco, Giulia; Taglialatela-Scafati, Orazio; Zinzula, Luca; Maccioni, Elias; Corona, Angela; Tramontano, EnzoBIOCHEMISTRY
Onopordum illyricum L., a Mediterranean plant, as a source of anti HIV-1 compounds2018Sanna, C.; Rigano, D.; Cortis, P.; Corona, A.; Ballero, M.; Parolin, C.; Del Vecchio, C.; Chianes...e, G.; Saccon, E.; Formisano, C.; Tramontano, E.; Esposito, F.PLANT BIOSYSTEMS
Antiviral Agents Against Ebola Virus Infection: Repositioning Old Drugs and Finding Novel Small Molecules2018Fanunza, Elisa; Frau, Aldo; Corona, Angela; Tramontano, EnzoANNUAL REPORTS IN MEDICINAL CHEMISTRY
Use of a Dual Luciferase Cell-Based Drug Screening Assay to Study VP24 Inhibition of JAK/STAT Pathway and its Reversion by Compounds2018Fanunza, Elisa; Frau, Aldo; Sgarbanti, Marco; Orsatti, Roberto; Corona, Angela; Tramontano, Enzo
Insights into the homo-oligomerization properties of N-terminal coiled-coil domain of Ebola virus VP35 protein2018Ramaswamy, VENKATA KRISHNAN; DI PALMA, Francesco; Vargiu, Attilio V.; Corona, Angela; Piano, Dari...o; Ruggerone, Paolo; Zinzula, Luca; Tramontano, EnzoVIRUS RESEARCH
Structure-guided approach identifies a novel class of HIV-1 Ribonuclease H inhibitors: Binding mode insights through magnesium complexation and site-directed mutagenesis studies2018Poongavanam, Vasanthanathan; Corona, Angela; Svendsen, Casper; Scipione, Luigi; Grandi, Nicole; P...andolfi, Fabiana; Di Santo, Roberto; Costi, Roberta; Esposito, Francesca; Tramontano, Enzo; Kongsted, JacobMEDCHEMCOMM
Chelation motifs affecting metal-dependent viral enzymes: N′-acylhydrazone ligands as dual target inhibitors of HIV-1 Integrase and Reverse Transcriptase Ribonuclease H domain2017Carcelli, Mauro; Rogolino, Dominga; Gatti, Anna; Pala, Nicolino; Corona, Angela; Caredda, Alessia...; Tramontano, Enzo; Pannecouque, Christophe; Naesens, Lieve; Esposito, FrancescaFRONTIERS IN MICROBIOLOGY
Natural product-inspired esters and amides of ferulic and caffeic acid as dual inhibitors of HIV-1 reverse transcriptase2017Sonar, Vijay P.; Corona, Angela; Distinto, Simona; Maccioni, Elias; Meleddu, Rita; Fois, Benedett...a; Floris, Costantino; Malpure, Nilesh V.; Alcaro, Stefano; Tramontano, Enzo; Cottiglia, FilippoEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Through scaffold modification to 3,5-diaryl-4,5-dihydroisoxazoles: new potent and selective inhibitors of monoamine oxidase B2017Meleddu, Rita; Distinto, Simona; Cirilli, Roberto; Alcaro, Stefano; Yanez, Matilde; Sanna, Maria ...Luisa; Corona, Angela; Melis, Claudia; Bianco, Giulia; Matyus, Peter; Cottiglia, Filippo; Maccioni, EliasJOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
Natural Product Kuwanon-L Inhibits HIV-1 Replication through Multiple Target Binding2017Martini, Riccardo; Esposito, Francesca; Corona, Angela; Ferrarese, Roberto; Ceresola, Elisa Rita;... Visconti, Laura; Tintori, Cristina; Barbieri, Alessandro; Calcaterra, Andrea; Iovine, Valentina; Canducci, Filippo; Tramontano, Enzo; Botta, MaurizioCHEMBIOCHEM
Isatin thiazoline hybrids as dual inhibitors of HIV-1 reverse transcriptase2017Meleddu, Rita; Distinto, Simona; Corona, Angela; Tramontano, Enzo; Bianco, Giulia; Melis, Claudia...; Cottiglia, Filippo; Maccioni, EliasJOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
Multi-target activity of Hemidesmus indicus decoction against innovative HIV-1 drug targets and characterization of Lupeol mode of action2017Esposito, Francesca; Mandrone, Manuela; Del Vecchio, Claudia; Carli, Ilaria; Distinto, Simona; Co...rona, Angela; Lianza, Mariacaterina; Piano, Dario; Tacchini, Massimo; Maccioni, Elias; Cottiglia, Filippo; Saccon, Elisa; Poli, Ferruccio; Parolin, Cristina; Tramontano, EnzoPATHOGENS AND DISEASE
N-Acylbenzenesulfonamide dihydro-1,3,4-oxadiazole hybrids: seeking selectivity toward carbonic anhydrase isoforms2017Bianco, Giulia; Meleddu, Rita; Distinto, Simona; Cottiglia, Filippo; Gaspari, Marco; Melis, Claud...ia; Corona, Angela; Angius, Rossella; Angeli, Andrea; Taverna, Domenico; Alcaro, Stefano; Leitans, Janis; Kazaks, Andris; Tars, Kaspars; Supuran, Claudiu T.; Maccioni, EliasACS MEDICINAL CHEMISTRY LETTERS
Design, synthesis and antiviral evaluation of novel heteroarylcarbothioamide derivatives as dual inhibitors of HIV-1 Reverse transcriptase-associated RNase H and RDDP functions2017Corona, Angela; Onnis, Valentina; Deplano, Alessandro; Bianco, Giulia; Demurtas, Monica; Distinto..., Simona; Cheng, Yung Chi; Alcaro, Stefano; Esposito, Francesca; Tramontano, EnzoPATHOGENS AND DISEASE
Exploring the thiazole scaffold for the identification of new agents for the treatment of fluconazole resistant Candida2016Meleddu, Rita; Distinto, Simona; Corona, Angela; Maccioni, Elias; Arridu, Antonella; Melis, Claud...ia; Bianco, Giulia; Matyus, Peter; Cottiglia, Filippo; Sanna, Adriana; DE LOGU, AlessandroJOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
Ribonuclease H/DNA polymerase HIV-1 reverse transcriptase dual inhibitor: mechanistic studies on the allosteric mode of action of isatin-based compound RMNC62016Corona, A; Meleddu, R; Esposito, F; Distinto, S; Bianco, G; Masaoka, T; Maccioni, E; Menéndez-Ari...as, L; Alcaro, S; Le Grice, SFJ; Tramontano, EPLOS ONE
New insights into the interaction between pyrrolyl diketoacids and HIV-1 integrase active site and comparison with RNase H2016Corona, Angela; di Leva, Francesco Saverio; Rigogliuso, Giuseppe; Pescatori, Luca; Madia, Valenti...na Noemi; Subra, Frederic; Delelis, Olivier; Esposito, Francesca; Cadeddu, Marta; Costi, Roberta; Cosconati, Sandro; Novellino, Ettore; di Santo, Roberto; Tramontano, EnzoANTIVIRAL RESEARCH
Studies on Cycloheptathiophene-3-carboxamide Derivatives as Allosteric HIV-1 Ribonuclease H Inhibitors2016Corona, Angela; Desantis, Jenny; Massari, Serena; Distinto, Simona; Masaoka, Takashi; Sabatini, S...tefano; Esposito, Francesca; Manfroni, Giuseppe; Maccioni, Elias; Cecchetti, Violetta; Pannecouque, Christophe; Le Grice, Stuart F J; Tramontano, Enzo; Tabarrini, OrianaCHEMMEDCHEM
Inhibitory effect of 2,3,5,6-tetrafluoro-4-[4-(Aryl)-1H-1,2,3-triazol-1-yl]benzenesulfonamide derivatives on HIV reverse transcriptase associated rnase H activities2016Pala, Nicolino; Esposito, Francesca; Rogolino, Dominga; Carcelli, Mauro; Sanna, Vanna; Palomba, M...ichele; Naesens, Lieve; Corona, Angela; Grandi, Nicole; Tramontano, Enzo; Sechi, MarioINTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Inhibition of HIV-1 reverse transcriptase dimerization by small molecules2016Tintori, C; Corona, A; Esposito, F; Brai, A; Grandi, N; Ceresola, ER; Clementi, M; Canducci, F; T...ramontano, E; Botta, MCHEMBIOCHEM
   
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